{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-3M8LK3KR/93977336-2892-4326-a703-255ef8b06164/HTML","dcterms:extent":"36 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-3M8LK3KR/a7f63941-0b2d-406c-8910-f7b71a36f647/PDF","dcterms:extent":"866 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-3M8LK3KR/bc737278-aba3-4be0-9d01-d58431f61849/TEXT","dcterms:extent":"29 KB"}],"edm:TimeSpan":{"@rdf:about":"2000-2024","edm:begin":{"@xml:lang":"en","#text":"2000"},"edm:end":{"@xml:lang":"en","#text":"2024"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:DOC-3M8LK3KR","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-fzwbu7gu"},{"@xml:lang":"sl","#text":"Image analysis and stereology"}],"dcterms:issued":"2005","dc:creator":["Elie, Nicolas","Herlin, Paulette","Labiche, Alexandre","Michels, Jean-Jacques"],"dc:format":[{"@xml:lang":"sl","#text":"številka:2"},{"@xml:lang":"sl","#text":"letnik:24"},{"@xml:lang":"sl","#text":"9 strani"},{"@xml:lang":"sl","#text":"str. 85-93"}],"dc:identifier":["ISSN:1580-3139","COBISSID:20112089","URN:URN:NBN:SI:doc-3M8LK3KR"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Društvo za stereologijo in kvantitativno analizo slike, Medicinska fakulteta"},"dc:subject":[{"@xml:lang":"en","#text":"Image Processing, Computer-Assisted"},{"@xml:lang":"sl","#text":"Jajčnik, novotvorbe"},{"@xml:lang":"sl","#text":"jajčniki"},{"@xml:lang":"en","#text":"Microscopy, Electron, Scanning"},{"@xml:lang":"sl","#text":"Mikroskopija elektronska, vrstična"},{"@xml:lang":"en","#text":"Ovarian Neoplasms"},{"@xml:lang":"sl","#text":"rak (medicina)"},{"@xml:lang":"sl","#text":"Slika, obdelava z računalnikom"},{"@xml:lang":"sl","#text":"stereologija"},{"@xml:lang":"en","#text":"Stromal Cells"},{"@xml:lang":"sl","#text":"Stromalne celice"},{"@rdf:resource":"http://www.wikidata.org/entity/Q16154261"}],"dcterms:temporal":{"@rdf:resource":"2000-2024"},"dc:title":{"@xml:lang":"sl","#text":"Control of low-resolution scanning of ovarian tumor stromal compartment|"},"dc:description":{"@xml:lang":"sl","#text":"The active search for markers of prognostic impact and therapeutic response isof crucial importance in oncology. The amount of stroma is a potential indicator with a significant impact on tumor growth. To solve the problems linked to tumor heterogeneity and, hence, of quantization at the microscopic level, we developed an image-analysis strategy dedicated to estimating the proportion of tumor connective tissue in whole histological sections at low resolution. 2,700-dot-per-inch numerical images were acquired with a calibrated slide scanner and automatically analyzed. We performed a quality control in order to evaluate the efficiency of the proposed method of analysisat the selected resolution. The point-counting method and the interactive drawing of stroma limits on equivalent mosaic microscopic images were \"the gold standards.\" The proportions of stroma estimated on microscopic images (magnification with a 4x objective corresponding to 16,200 dots per inch) and on slide scanner images (2,700 dots per inch) through point countingstereology or manual delineation were equivalent (p < 0.0001). The results obtained through automatic image processing of scanner images were also close to the gold standard (95% correlation, p < 0.0001). The proposed method makes it possible to estimate the stroma amount of ovarian carcinomas in whole histological sections with a simple, fast, and low-cost acquisition device"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:DOC-3M8LK3KR","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:DOC-3M8LK3KR"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:DOC-3M8LK3KR/a7f63941-0b2d-406c-8910-f7b71a36f647/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Društvo za stereologijo in kvantitativno analizo slike"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:DOC-3M8LK3KR/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:DOC-3M8LK3KR"}}}}