38 KB481 KB35 KB192920262012Domanovič, DragoslavStecher, AdelaZver, Samoštevilka:1letnik:81str. 7-15ISSN:1318-0347COBISSID:29485017URN:URN:NBN:SI:doc-RZZC9Y4RslSlovensko zdravniško društvoZdravniški vestnikAbo Blood-Group SystemABO sistem krvnih skupinAfibrinogenemiaAfibrinogenemijaBlood Coagulation DisordersBlood Grouping And CrossmatchingBlood TransfusionChemistryCryoglobulinsCryopreservationKrioglobuliniKrioshranjevanjeKrvna koagulacija, motnjeKrvna transfuzijaKrvne skupine in navzkrižno določanjePlasmaPlazmaPractice GuidelinesPraktična navodilaPurpura trombotična, trombocitopeničnaPurpura, Thrombotic ThrombocytopenicPriporočila za uporabo in zdravljenje s svežo zmrznjeno plazmo| Recommendations for the usage and treatment with fresh frozen plasma|Fresh frozen plasma (FFP) is a blood component obtained from processed whole blood or collected by plasmapheresis and afterwards stored in frozen state. Indications for the clinical use of FFP are single coagulation factor deficiencies (such as F V and F XI), multiple coagulation factors deficiency (most frequent as a consequence of massive hemorrhage), coagulopathy caused byadvanced liver disease, warfarin mediated coagulopathy and thrombotic thrombocytopenic purpura. Standard FFP treatment dose in mentioned indicationsis generally 10-20 ml/kg of patient body weight. During the treatment attention should be paid to possible FFP treatment related adverse effects. Most frequent are allergic reactions. We should not consider FFP as atreatment approach in clinical situations where equally effective and safer treatment modalities are availableTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo