{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-197RQBLO/0324cc80-51b2-42f1-a9a6-60ae5bcf6c45/HTML","dcterms:extent":"38 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-197RQBLO/3426d85c-e9d3-48c7-b688-73090e626ecf/PDF","dcterms:extent":"134 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-197RQBLO/2d8f739b-6a7f-4af7-aacc-365b7b343297/TEXT","dcterms:extent":"24 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-197RQBLO","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2008","dc:creator":["Ćeranić, Davorin","Glumbić, Ivana","Kavalar, Rajko","Knehtl, Maša","Skalicky, Marjan","Skok, Pavel","Urlep, Dejan"],"dc:format":[{"@xml:lang":"sl","#text":"številka:2"},{"@xml:lang":"sl","#text":"5 strani"},{"@xml:lang":"sl","#text":"letnik:77"},{"@xml:lang":"sl","#text":"str. 135-139"}],"dc:identifier":["ISSN:1318-0347","COBISSID:2894655","URN:URN:NBN:SI:doc-197RQBLO"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"Amiloidoza"},{"@xml:lang":"en","#text":"Amyloidosis"},{"@xml:lang":"sl","#text":"bolezni"},{"@xml:lang":"en","#text":"complications"},{"@xml:lang":"en","#text":"disease"},{"@xml:lang":"sl","#text":"Etiologija"},{"@xml:lang":"en","#text":"etiology"},{"@xml:lang":"sl","#text":"jetra"},{"@xml:lang":"sl","#text":"Jetra, bolezni"},{"@xml:lang":"sl","#text":"jetrna amiloidoza"},{"@xml:lang":"en","#text":"Liver Diseases"},{"@xml:lang":"en","#text":"pathology"},{"@xml:lang":"sl","#text":"Patologija"},{"@xml:lang":"en","#text":"therapy"},{"@xml:lang":"sl","#text":"Zapleti"},{"@xml:lang":"sl","#text":"zdravljenje"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Jetrna amiloidoza - predstavitev bolnika in pregled literature| Hepatic amyloidosis - case report and literature review|"},"dc:description":[{"@xml:lang":"sl","#text":"Background. Amyloidosis is a disorder of protein metabolism that leads to extracellular deposition of insoluble proteinaceous material. Clinically important are amyloidosis AL and AA. Primary of AL form is associated with immunocyte dyscrasia, multiple myeloma, macroglobulinemia or monoclonal gammopathy, the precursor protein are immunoglobulin light chains. Amyloidosis AA or reactive amyloidosis is associated with chronic inflammatory disease. Patients and methods. The autors are presenting a 52-year old man who was transferred to their department for diagnostic proceedings of anemia and liver disease from the department of orthopaedics, where he was treated for compression fractures of the spine. Unfortunately during the first hospitalisation the patient refused liver biopsy. The patient died due to spleenic rupture and exsanguination into abdominal cavity. At autopsy, amyloidosis was found with amyloid deposits in the liver and other organs. In the article, different forms of this disease with grim prognosis are described. Conclusions. The authors presented a patient with primary amyloidosis which led to fatal complication. According to the literature, patients with this form of amyloidosis have median survival of 1 - 2 years from establishing the diagnosis"},{"@xml:lang":"sl","#text":"Amiloidoza je skupina bolezni, za katere je značilno zunajcelično odlaganje amiloida. Klinično sta najpomembnejši in najpogostejši amiloidoza AL in amiloidoza AA. Amilodiozo AL najdemo največkrat v sklopu primarne amiloidoze, plazmocitoma, ali B-celičnega limfoma, proteinski predhodnik so lahko verige imunoglobulinov. Amiloidozo AA poznamo kot sekundarno ali reaktivno in je posledica osnovne vnetne bolezni. Bolniki in metode. V prispevku avtorji predstavljamo 52-letnega bolnika, ki smo ga obravnavali zaradi neopredeljene jetrne bolezni in slabokrvnosti, ugotovljene ob zdravljenju patoloških zlomov vretenc. Žal med prvim zdravljenjem ni pristal na jetrno biopsijo za pojasnitev narave jetrne bolezni. Posmrtno je bila ugotovljena amiloidoza, ki je prizadela jetra in druge organe. Neposredni vzrok smrti je bilo raztrganje vranice in izkrvavitev v trebušno votlino. Opisane so oblike amiloidoze, ki običajno predstavljajo bolezen z neugodnim potekom. Zaključki. Predstavili smo bolnika z redko obliko primarne amiloidoze, ki je bila vzrok usodnega zapleta. Po podatkih iz literature je preživetje teh bolnikov 1 - 2 leti od ugotovitve bolezni"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-197RQBLO","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-197RQBLO"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-197RQBLO/3426d85c-e9d3-48c7-b688-73090e626ecf/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-197RQBLO/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-197RQBLO"}}}}