686 KB33 KB199220251999Čemažar, Majaštevilka:2letnik:33str. 127-136ISSN:1318-2099COBISSID:9970649URN:URN:NBN:SI:doc-19C0IGATslCroatian Medical Association - Croatian Society of RadiologySlovenian Medical Society - Section of RadiologyRadiology and oncology (Ljubljana)AnoxiaCell deathCell survivalChromosomesDna damageDrug therapyGene expressionkemoterapijaMiceMicronucleus testsNeoplasmsprognozaRadiation effectsRadiation injuriesradioterapijaRadiotherapySarcoma, experimentalTreatment outcometumorjizdravljenjePredictive assays of tumor response to chemo and radiotherapy| Napovedni testi za izid zdravljenja tumorjev po kemo in radioterapiji|Currently used predictive assays of treatment outcome of tumors treated by chemo- or radiotherapy and radiation damage of normal tissues are presented. This review is focused on the assays where tumor cells derived from the human tumors need to be cultured in in vitro conditions to perform the test. In addition, an overview of the clinical studies dealing with the correlation between predictive assays and treatment out-come or radiation damage to the normal tissues is givenPredstavljeni so testi za napovedovanje izida zdravljenja tumorjev po kemo- inradioterapiji in poškodb normalnih tkiv po radioterapiji. Pregled je osredotočen na tiste teste, pri katerih je treba celice gojiti v pogojih in vitro. Poleg tega članek obravnava tudi korelacijo med napovednimi testi in izidom zdravljenja različnih vrst raka ter poškodbami normalnih tkivTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaOnkološki inštitut Ljubljana