127 KB29 KB192920262016Jeverica, SamoKolenc, UršaLozar Krivec, JanaLučovnik, MihaTul, Natašaštevilka:7/8letnik:85str. 393-400ISSN:1318-0347COBISSID:33011673URN:URN:NBN:SI:doc-2YHN7PBPslSlovensko zdravniško društvoZdravniški vestnikbakterijske infekcijeneonatal infectionsneonatalne okužbenosečnostpregnancyStreptococcus agalactiaePrevalenca kolonizacije z bakterijo Streptococcus agalactiae pri nosečnicah v Sloveniji v obdobju 2013-2014| Prevalence of Streptococcus agalactiae colonisation among pregnant women in Slovenia, 2013-2014|Background: Streptococcus agalactiae is the leading cause of preventable invasive neonatal infections. Detection of maternal colonisation and use of antimicrobial prophylaxis during labour is a standard preventative approach. Very few data about the prevalence of colonisation with S. agalactiae among pregnant women in Slovenia are available. Methods: We performed a retrospective study of consecutive samples from pregnant women screened for S. agalactiae colonisation with enrichment culture during the period 2013-2014. Basic demographic data, specimen type, timing and result of the assay were analysed. Cumulative antimicrobial susceptibility for the positive samples was calculated. Results: During 2 years study period 1564 pregnant women were tested. Mean age 31 years (18-46 years). Among samples received, majority were vaginal swabs 57,0 % (n=893). Recommended combined vaginal-rectal swabs were received in 12,9 % (n=192). Overall prevalence of maternal colonisation was 17,1 % (n=268) and did not differ with regard to specimen type. Resistance or reduced susceptibility to erythromycin and clindamycin was 23,1 % (n=62) and 20,9 % (n=56), respectively. No resistance to penicillin and vancomycin was detected. Conclusions: Few pregnant women get screened for S. agalactiae in Slovenia. Nevertheless, high colonisation rate was detected on a large sample size. Most samples were taken during the proposed period between 35-37 week of pregnancy. Recommended combined vaginal-rectal were less frequently taken for screening than vaginal swabs only. Penicillin and vancomycin remains universally active against S. agalactiae. However, erythromycin and clindamycin resistance was highTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo