{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-3F9OOFKM/58449be1-f619-4549-aa65-ef0161a3628a/HTML","dcterms:extent":"22 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-3F9OOFKM/fd662350-a12e-41a3-9b39-726db0baea51/PDF","dcterms:extent":"476 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-3F9OOFKM/eb884dd5-389a-4ccb-9866-ea92a3424aa6/TEXT","dcterms:extent":"18 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-3F9OOFKM","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2012","dc:creator":["Ferlan-Marolt, Vera","Hafner, Matjaž","Kikec, Zdenko","Vujasinović, Miroslav"],"dc:format":[{"@xml:lang":"sl","#text":"letnik:81"},{"@xml:lang":"sl","#text":"številka:9"},{"@xml:lang":"sl","#text":"str. 676-680"}],"dc:identifier":["ISSN:1318-0347","COBISSID:30237913","URN:URN:NBN:SI:doc-3F9OOFKM"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"en","#text":"Adult"},{"@xml:lang":"en","#text":"Adverse Effects"},{"@xml:lang":"sl","#text":"bolezni jeter"},{"@xml:lang":"en","#text":"Chemically Induced"},{"@xml:lang":"en","#text":"Cholestasis, Intrahepatic"},{"@xml:lang":"sl","#text":"Ciprofloksacin"},{"@xml:lang":"en","#text":"Ciprofloxacin"},{"@xml:lang":"en","#text":"drug"},{"@xml:lang":"sl","#text":"Holestaza intrahepatična"},{"@xml:lang":"sl","#text":"jetra"},{"@xml:lang":"sl","#text":"Jetra, bolezni"},{"@xml:lang":"en","#text":"Liver Diseases"},{"@xml:lang":"sl","#text":"Odrasli"},{"@xml:lang":"sl","#text":"stranski učinki"},{"@xml:lang":"sl","#text":"zdravila"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"S ciprofloksacinom povzročena holestatska okvara jeter| a case report| Ciprofloxacin-induced cholestatic liver injury| prikaz primera|"},"dc:description":{"@xml:lang":"sl","#text":"Background: Drug-induced liver injury has been described for a large number ofdrugs. It is a common cause of drug withdrawal from the market. Ciprofloxacin is a commonly prescribed fluoroquinolone antibiotic and is a rare cause of hepatotoxicity. To our best knowledge this is the first case of ciprofloxacin-induced cholestatic liver injury in Slovenia. Case report: A 19year old man has been treated with ciprofloxacin at a daily dose of 500 mg twice a day due to a mild respiratory infection. After twenty days he was admitted to hospital because of jaundice. Laboratory findings showed a typicalpattern of acute cholestatic liver failure, which was additionally confirmed by the liver biopsy. The patient was treated symptomatically. Ten months later the patientćs clinical status is stabile with a normal bilirubin level and mildly elevated alkaline phosphatase and gamma-glutamyltransferase. Conclusion: Although severe hepatotoxicity after the administration of ciprofloxacin is rare, physicians should be cautious and alert to its side-effects"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-3F9OOFKM","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-3F9OOFKM"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-3F9OOFKM/fd662350-a12e-41a3-9b39-726db0baea51/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-3F9OOFKM/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-3F9OOFKM"}}}}