257 KB19 KB199220251998Donaldson, Craig W.Lee, Jeffrey R.Orner, James B.Proulx, Gary M.letnik:32številka:4str. 401-406ISSN:1318-2099COBISSID_HOST:8142297URN:URN:NBN:SI:doc-84KPRON8enCroatian Medical Association - Croatian Society of RadiologySlovenian Medical Society - Section of RadiologyRadiology and oncology (Ljubljana)AdultAdverse effectsBreast neoplasmsLupus erythematosus, systemicRadiotherapySystemic lupus erythematosus diagnosed with extreme skin reaction during radiation therapy: a case report| Sistemski lupus eritematodes z izrazito kožno reakcijo med radioterapijo: prikaz primera|The use of breast conservation therapy in patients with collagen vascular disease is controversial. Initial reports demonstrated severe skin reactions in patients receiving radiotherapy who also had a diagnosis of systemic lupus erythematosus or sclerederma. However, a more recent case-control study found no increased incidence of complications in these patients compared to patientswithout collagen vascular disease. We report a case of a patient diagnosed with systemic lupus erythematosus after developing a severe skin reaction early during her course of breast radiotherapy. The clinical course of the patient is reviewed along with the controversies surrounding this clinical dilemnaŠe vedno si nasprotujejo mnenja o konzervirajočem zdravljenju bolnic s karcinomom dojke, ki imajo tudi kolagensko vaskulatorno bolezen. Poročali so že o resnih kožnih reakcijah pri bolnicah, ki so jih obsevali in so imele sistemski lupus eritematodes ali sklerodermo. Novejša študija primerov s kontrolami pa pri teh bolnicah ne kaže večjega števila komlikacij kot pri tistih brez kolagenske vaskulatorne bolezni. Prikazujemo primer bolnice, ki smo ji diagnosticirali sistemski lupus eritematodes kmalu po začetku obsevanjadojke, ker je razvila resno kožno reakcijo. Opisujemo klinični potek zdravljenja, ob njem pa tudi nasprotujoče dejavnike ter klinične dilemeTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaOnkološki inštitut Ljubljana