44 KB1206 KB34 KB200520132011Benedičič, MitjaBošnjak, Romanletnik:16številka:33str. 3-11ISSN:1318-8941COBISSID:28549849URN:URN:NBN:SI:doc-AXH0BGUNenSlovensko zdravniško društvoEndoskopska revijaadenomhipofizanosna kostnovotvorbetumorEndoscopic endonasal approach to pituitary adenoma with invasion to the cavernous sinus| Endoskopska endonazalna odstranitev hipofiznega adenoma s širjenjem v kavernozni sinus|Introduction. Transsphenoidal removal is the first-choice treatment for pituitary adenoma. Endoscopic view and dedicated instruments allow for removalof invasive adenomas from different cavernous sinus compartments. Patients and methods. Thirteen patients with intraoperatively confirned pituitary adenoma invading the cavernous sinus were enroled in the study. Middle turbinectomy and posterior ethmoidectomy permitted maximal anterior sphenoidotomy and lateral exposure of the sphenoid sinus, and allowed drillingof the lateral wall of sphenoid toward the orbital apex and unroofing of the superior orbital fissure and foramen rotundum. A neuronavigational system was used for surgical planning. Results. The patients were followed up for 14.6 months (range 3-40 months). Vision improved in 4/13 patients; in the rest it remained normal or was as good as before surgery. Small residual tumors were seen or suspected in 5/13 patients (subtotal removal > 90%). The preoperative level of pituitary function was preserved in 11/13 cases. All secretory adenomas were either cured or controlled with pharmacological agentsTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo, Združenje za endoskopsko kirurgijo