<?xml version="1.0"?><rdf:RDF xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:edm="http://www.europeana.eu/schemas/edm/" xmlns:wgs84_pos="http://www.w3.org/2003/01/geo/wgs84_pos" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:rdaGr2="http://rdvocab.info/ElementsGr2" xmlns:oai="http://www.openarchives.org/OAI/2.0/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:ore="http://www.openarchives.org/ore/terms/" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:dcterms="http://purl.org/dc/terms/"><edm:WebResource rdf:about="http://www.dlib.si/stream/URN:NBN:SI:doc-CIBTXI71/6bda0f74-5764-435d-b5e8-bf164b742f35/PDF"><dcterms:extent>212 KB</dcterms:extent></edm:WebResource><edm:WebResource rdf:about="http://www.dlib.si/stream/URN:NBN:SI:doc-CIBTXI71/d30a2bb7-d0df-44f5-95b0-d067ee6a5e26/TEXT"><dcterms:extent>13 KB</dcterms:extent></edm:WebResource><edm:TimeSpan rdf:about="1992-2025"><edm:begin xml:lang="en">1992</edm:begin><edm:end xml:lang="en">2025</edm:end></edm:TimeSpan><edm:ProvidedCHO rdf:about="URN:NBN:SI:doc-CIBTXI71"><dcterms:isPartOf rdf:resource="https://www.dlib.si/details/URN:NBN:SI:spr-FNIFVE9S" /><dcterms:issued>2000</dcterms:issued><dc:creator>Čufer, Tanja</dc:creator><dc:format xml:lang="sl">številka:3</dc:format><dc:format xml:lang="sl">letnik:34</dc:format><dc:format xml:lang="sl">str. 285-288</dc:format><dc:identifier>COBISSID:11945689</dc:identifier><dc:identifier>ISSN:1318-2099</dc:identifier><dc:identifier>URN:URN:NBN:SI:doc-CIBTXI71</dc:identifier><dc:language>en</dc:language><dc:publisher xml:lang="sl">Croatian Medical Association - Croatian Society of Radiology</dc:publisher><dc:publisher xml:lang="sl">Slovenian Medical Society - Section of Radiology</dc:publisher><dcterms:isPartOf xml:lang="sl">Radiology and oncology (Ljubljana)</dcterms:isPartOf><dc:subject xml:lang="sl">Axilla</dc:subject><dc:subject xml:lang="sl">Breast neoplasms</dc:subject><dc:subject xml:lang="sl">dojke</dc:subject><dc:subject xml:lang="sl">Lymph node excision</dc:subject><dc:subject xml:lang="sl">rak (medicina)</dc:subject><dc:subject xml:lang="sl">Therapy</dc:subject><dc:subject xml:lang="sl">zdravljenje</dc:subject><dcterms:temporal rdf:resource="1992-2025" /><dc:title xml:lang="sl">Do we need axillary dissection in early breast cancer?|</dc:title><dc:description xml:lang="sl">Background. In the existing paradigm of the invasive breast cancer, the treatment with the axillary lymphnode dissection (ALND) and histologic stagingof the axilla, which is associated with a substantial morbidity, is considered necessary for the treatment decision and local control of disease. However paradigms are changing and, since primary tumor characteristics are increasingly used for treatment decision and since there is a trend towards the broad application of preoperative chemotherapy, ALND is less and less important for the treatment planning. In a small subgroup of patients in whom the information on nodal status is still important it can be obtained accurately by the sentinel lymph node biopsy. For good local control of the disease, ALND can be replaced with irradiation of the axilla with substantially lesser morbidity. Conclusions. Abandoning ALND together with breast conserving surgery is one of the major steps towards less mutilating surgery leading to a better quality of life of breast cancer patients at the end of this millennium</dc:description><dc:description xml:lang="sl">Izhodišča. Popolna odstranitev pazdušnih bezgavk (POPB) s histološkim pregledom le-teh še vedno velja za potreben kirurški poseg v okviru zdravljenja omejenega raka dojk. Ta poseg, ki ima pogosto neželene kasne podsledice, naj bi bil potreben za odločitev o dopolnilnem sistemskem zdravljenju in za lokalno kontrolo bolezni. Vedno bolj pa se zastavlja vprašanje, ali je temu res tako. Glede na to, da se dopolnilno zdravljenje vedno bolj načrtuje na podlagi bioloških lastnosti prvotnega tumorja in zaradivse pogostejše uporabe predoperativnega sistemskega zdravljenja, je POPB vse manj pomembna za načrtovanje zdravljenja. Pri majhni skupini bolnic, pri katerih pa je za izbor dopolnilnega zdravljenja še vedno potrebna informacija o prizadetosti pazdušnih bezgavk s tumorjem, lahko POPB nadomesti biopsija varovalne bezgavke. Dobro lokalno kontrolo bolezni je ob manjših kasnih posledicah mogoče doseči tudi z obsevanjem pazduhe. Zaključki. Skupaj z ohranitvijo dojke je opustitev kirurške odstranitve vseh bezgavk v pazduhi eden glavnih korakov k izboljšanju kvalitete življenja bolnic z omejenim rakom dojk</dc:description><edm:type>TEXT</edm:type><dc:type xml:lang="sl">znanstveno časopisje</dc:type><dc:type xml:lang="en">journals</dc:type><dc:type rdf:resource="http://www.wikidata.org/entity/Q361785" /></edm:ProvidedCHO><ore:Aggregation rdf:about="http://www.dlib.si/?URN=URN:NBN:SI:doc-CIBTXI71"><edm:aggregatedCHO rdf:resource="URN:NBN:SI:doc-CIBTXI71" /><edm:isShownBy rdf:resource="http://www.dlib.si/stream/URN:NBN:SI:doc-CIBTXI71/6bda0f74-5764-435d-b5e8-bf164b742f35/PDF" /><edm:rights rdf:resource="http://rightsstatements.org/vocab/InC/1.0/" /><edm:provider>Slovenian National E-content Aggregator</edm:provider><edm:intermediateProvider xml:lang="en">National and University Library of Slovenia</edm:intermediateProvider><edm:dataProvider xml:lang="sl">Onkološki inštitut Ljubljana</edm:dataProvider><edm:object rdf:resource="http://www.dlib.si/streamdb/URN:NBN:SI:doc-CIBTXI71/maxi/edm" /><edm:isShownAt rdf:resource="http://www.dlib.si/details/URN:NBN:SI:doc-CIBTXI71" /></ore:Aggregation></rdf:RDF>