307 KB38 KB192920262022Krhlikar, NinaUmek, LanVidović Valentinčič, NatašaVidović Valentinčič, Natašaletnik:91številka:iss. 9/10str. 373-381DOI:10.6016/ZdravVestn.3349COBISSID_HOST:128739587ISSN:1318-0347URN:URN:NBN:SI:doc-CJL11NQWslSlovensko zdravniško društvoZdravniški vestnikdolgoročni potekintermediarni uveitisintermediate uveitislong-term follow upremisijaremissionDolgoročni potek in izid bolezni pri bolnikih z intermediarnim uveitisom s spremljanjem vsaj 20 let| Long term course and visual outcome in patients with intermediate uveitis with a follow up of at least 20 years|Background: Our study aimed to investigate the long-term course and visual outcome of intermediate uveitis (IU). Methods: We performed a retrospective cohort institutional study of patients with IU, first seen in our clinic between 1985 and 1995, with a follow-up of at least 20 years. Results: We studied 20/29 patients with IU for at least 20 years with a mean follow-up of 25.3 ± 2 years. Remission was ob - served in 17/20 patients with a completed follow-up of 20 years with a mean time to remission of 11.14 years (95% CI 7.94 - 14.34). After performing Kaplan Meier analysis, the systemic diagnosis was associated with a longer time to remission. Relapses of IU were observed in 6/17 patients after achieving remission with a mean time to relapse of 8.2 years (95% CI 2.8 - 13.6). After 20 years of follow-up, 11/39 eyes had developed visual loss. Cystoid macular oedema (CMO) with macular atrophy was associated with an increased risk for visual impairment. Conclusion: The visual prognosis of IU after 20 or more years of follow-up is favourable in most patients achieving remis - sion. However, the disease course of IU is long with frequent complications and possible relapse even after stable remis - sion for a longer periodis achieved. Regular long-term follow-up of patients with IU is importantTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo