244 KB18 KB192920262004Gajzer, BorutKoželj, MiranKrebs, Bojanletnik:73številka:7-8str. 589-592ISSN:1318-0347COBISSID_HOST:1656127URN:URN:NBN:SI:doc-CZ3C9GC1slSlovensko zdravniško društvoZdravniški vestnikColonic neoplasmsMortalitySurgical procedures, operativeSurvivalKirurško zdravljenje bolnikov z rakom debelega črevesa na Oddelku za abdominalno in splošno kirugijo Splošne bolnišnice Maribor v obdobju 1998 - 2001| Surgical treatment of patients with colon cancer in Department for abdominal and general surgery at Maribor general hospital in years 1998 - 2001|Background. The aim of this paper is to present and assess a surgical treatment of patients with colon cancer. Methods. All patients with colon cancer, who were operated in years 1998-2001, were included in the analysis. We have collected data including patients age, localization and stage of cancer, types of preformed procedures, postoperative mortality, disease recurrence and survival of the patients. Results. We have operated on 308 patients with histological evidence of colon cancer in above mentioned period. The average patients age was 66.5 years (SD = 11.1; 95% CI: 44.3-88.7). Primary tumor was most commonly (36%) located in sigmoid colon. UICC stages were as follows: stage I 34 patients, 11%; stage II 141, 46%; stage III 64, 21%; stage IV 69, 22%. We have performed 287 resections of colon (93% resectabillity), of these 214 (75%) were potentially curative R0 resections. Share of urgent procedures was 21%. In the postoperative period 22 patients (7%) have died. Postoperative mortality was significantly higher by urgent (19%) compared to scheduled procedures (4%) (chi sup2 = 16; df = 1; p = 0,005). In the observed time 22% of patients developed recurrent cancer. Mean survival rate of our patients was 1274 days or 3.5 years (SD = 191; 95% CI: 900-1648). Calculated overall five years survival rate was 45%. Conclusions. Planned and registered surgical treatment of patients with colon cancer, surgical specialization in colon surgery and adjuvant oncological treatment have shown the same incentive results, reflected in increased survival rateIzhodišča. Namen pričujoeega dela je prikazati in ovrednotiti kirurško zdravljenje bolnikov z rakom debelega črevesa. Metode. V analizo smo vključili vse bolnike z rakom debelega črevesa (RDE), operirane v letih 1998-2001. Zbrali smo podatke o starosti bolnikov, umestitvi in stadiju rakov, vrstah operacij, pooperativni smrtnosti, ponovitvah bolezni in preživetju teh bolnikov. Rezultati. V omenjenem obdobju smo operirali 308 bolnikov s histološko dokazanim rakom debelega črevesa. Povprečna starost bolnikov je bila 66,5 leta (SD = 11,1; 95% IZ: 44,3-88,7). Primarni tumor je bil največkrat (36%) v sigmoidnem delu kolona. Razporeditev po klasifikaciji UICC je bila: stadij I 34 bolnikov, 11%; stadij II 141, 46%; stadij III 64, 21%; stadij IV 69, 22%. Naredili smo 287 resekcij debelega črevesa (93-odstotna resektabilnost), od tega 214 (75%) potencialno ozdravljenih resekcij R0. Delež urgentnih operacij je bil 21%. V pooperativnem obdobju je umrlo 22 bolnikov (7%). Pooperativna smrtnost je bila statistično značilno višja pri urgentnih posegih (19%) v primerjavi s programsko operiranimi bolniki (4%) (hi na 2 = 16; df = 1; p = 0,005). V opazovanem času po posegu je pri 22% bolnikov prišlo do ponovitve bolezni. Srednje preživetje naših bolnikov je 1274 dni ali 3,5 leta (SD = 191č 95% IZ: 900-1648). Izračunano celokupno petletno preživetje znaša 45%. Zaključki. Dobro zastavljeno in protokolirano zdravljenje bolnikov z RDE, usmerjanje kirurgov v ožje področje kolorektalne kirurgije in adjuvantno onkološko zdravljenje dajejo spodbudne rezultate, ki se zrcalijo v boljšem preživetju bolnikovTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo