{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-DARVY6DW/bb713c2e-ad42-4fd0-8c33-453a12183157/HTML","dcterms:extent":"15 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-DARVY6DW/acf34af1-5063-49d1-b9c6-67934983de4d/PDF","dcterms:extent":"383 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-DARVY6DW/ce75cc7f-cf44-4c21-baed-b4cdd499a338/TEXT","dcterms:extent":"12 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-DARVY6DW","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2010","dc:creator":["Rylander, Ragnar","Salobir, Barbara","Terčelj-Zorman, Marjeta"],"dc:format":[{"@xml:lang":"sl","#text":"številka:12"},{"@xml:lang":"sl","#text":"4 strani"},{"@xml:lang":"sl","#text":"letnik:79"},{"@xml:lang":"sl","#text":"str. 825-828"}],"dc:identifier":["ISSN:1318-0347","COBISSID:27829209","URN:URN:NBN:SI:doc-DARVY6DW"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"en","#text":"Antifungal Agents"},{"@xml:lang":"sl","#text":"Antimikotiki"},{"@xml:lang":"en","#text":"Drug Therapy"},{"@xml:lang":"en","#text":"Sarcoidosis"},{"@xml:lang":"sl","#text":"Sarkoidoza"},{"@xml:lang":"en","#text":"therapy"},{"@xml:lang":"en","#text":"Treatment Outcome"},{"@xml:lang":"sl","#text":"zdravljenje"},{"@xml:lang":"sl","#text":"Zdravljenje, izid"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Anti-fungal medication and sarcoidosis| Antimikotiki in sarkoidoza|"},"dc:description":{"@xml:lang":"sl","#text":"Background: Previous studies on sarcoidosis have shown that the addition of ananti-fungal medication to the traditional treatment with corticosteroids improves treatment efficiency. It cannot be excluded that the effect is due toa stimulatory effect of the anti-fungal medication on the action of corticosteroids. To assess this possibility a study was undertaken where patients with sarcoidosis stage 2 were given an antifungal medication only. Material and methods: Study subjects (n=10) were recruited from newly diagnosed cases of sarcoidosis and observed for 3 months to reduce the risk ofincluding patients with spontaneous regression of the disease. They were given an anti-fungal medication for 2-11 months and x-rays were taken before and every second month after starting the treatment. Diffusion capacity, serumangiotensin converting enzyme, and chitotriosidase were determined as markers of sarcoidosis activity. Results: There were improvements in the x-rayfindings as well as the markers of sarcoidosis in 8 out of 10 patients. Two patients had an exacerbation of their disease after two months and they were given corticosteroids in addition to the anti-fungal medication. Comments: The results demonstrate that the beneficial effects of anti-fungal medication are specific and not caused by an improvement of corticosteroid efficacy. The findings provide a basis for larger clinical studies"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-DARVY6DW","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-DARVY6DW"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-DARVY6DW/acf34af1-5063-49d1-b9c6-67934983de4d/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-DARVY6DW/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-DARVY6DW"}}}}