{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-DLZHATOQ/decc99e8-3f43-4f0c-bbca-b0160c5da93a/HTML","dcterms:extent":"20 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-DLZHATOQ/c1182ca7-0108-4a97-9ee1-e3f63f951ef2/PDF","dcterms:extent":"112 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-DLZHATOQ/9d84001b-79a5-4547-9568-d4e15279f34e/TEXT","dcterms:extent":"19 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-DLZHATOQ","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2006","dc:creator":["Benko, Davorin","Fišer, Jerneja","Piltaver-Vajdec, Irena","Slemenik-Pušnik, Cirila","Tomič, Viktorija","Tretjak, Martin"],"dc:format":[{"@xml:lang":"sl","#text":"številka:12"},{"@xml:lang":"sl","#text":"4 strani"},{"@xml:lang":"sl","#text":"letnik:75"},{"@xml:lang":"sl","#text":"str. 829-832"}],"dc:identifier":["ISSN:1318-0347","COBISSID:22420441","URN:URN:NBN:SI:doc-DLZHATOQ"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"en","#text":"Adult"},{"@xml:lang":"sl","#text":"bakterijske infekcije"},{"@xml:lang":"en","#text":"Community-Acquired Infections"},{"@xml:lang":"en","#text":"Fatal Outcome"},{"@xml:lang":"en","#text":"Genetics"},{"@xml:lang":"sl","#text":"Infekcije, domačega okolja"},{"@xml:lang":"en","#text":"Isolation And Purification"},{"@xml:lang":"en","#text":"Leukocidins"},{"@xml:lang":"sl","#text":"Levkocidini"},{"@xml:lang":"sl","#text":"Odrasli"},{"@xml:lang":"sl","#text":"pljučnica"},{"@xml:lang":"sl","#text":"Pljučnica bakterijska"},{"@xml:lang":"en","#text":"Pneumonia, Bacterial"},{"@xml:lang":"sl","#text":"Smrtni izid"},{"@xml:lang":"en","#text":"Staphylococcus Aureus"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Staphylococcus aureus, nosilec gena za Panton-Valentine leukocidin, in letalna nekrotizirajoča pljučnica pri mladem imunokompetentnem bolniku| Lethal necrotising pneumonia in young imunocompetent patient caused by Staphyloccocus aureus carrying gene for Panton-Valentine leukocidin|"},"dc:description":[{"@xml:lang":"sl","#text":"Background Staphylococcus aureus (S. aureus) is a major cause of hospital-acquired infections. It secretes many exotoxins, in less then 5% alsoPanton-Valentine leukocidin (PVL). S. aureus carrying PVL genes is mainly associated with necrotic lesions of skin and mucosa and can cause severe necrotising community-acquired pneumonia. Methods We describe a case of a 30 year-old patient with a history of furunculosis who was admitted to our hospital with atypical lower abdominal pain. A clinical picture of acute abdomen developed and he was operated with no intraabdominal pathology found. A periprocedural respiratory insufficiency and later septic shock developed. S. aureus and Streptococcus pneumoniae were isolated from blood cultures and tracheal aspirate. In spite of all measures taken, high ventilatory support and targeted antibiotic treatment, severe pulmonary dysfunction with bilateralpneumothorax developed and the patient died of respiratory failure. Later genes encoding PVL were found in the isolated strains of S. aureus. Conclusions Severe progressive necrotising pneumonia with high mortality can be caused by PVL positive S. aureus in imunocompetent patients. To prevent thefuture spread of PVL positive S. aureus infection, the measures as known for methicillin-resistant S. aures, should probable be taken"},{"@xml:lang":"sl","#text":"Izhodišča Staphylococcus aureus (S. aureus) je nujpogostejši povzročitelj bolnišničnih okužb. Izloča številne eksotoksine, v manj kot 5% tudi Paraton-Valentine leukocidin (PVL). PVL pozitivni S. aureus je povezan z okužbami kože, lahko pa povzroča tudi hudo progresivno nekrotizirajočo pljučnico domačega okolja. Metode Opisujemo primer 30-letnega bolnika s furunkulozo, ki je zbolel z nejasnimi bolečinami v spodnjem delu trebuha in jebil zaradi klinične slike akutnega abdomna kasneje tudi operiran. V trebušnivotlini ni bilo znakov kirurške bolezni. Že med posegom je prišlo do respiratorne insuficience, kasneje se je ob tem razvila tudi slika septičnega šoka. Iz aspirata traheje in hemokultur smo osamili S. aureus in Streptococcuspneumoniae. Kljub vsem ukrepom z visoko podporo predihavanja in ciljani antibiotični terapiji je prišlo do hude parenhimske pljučne okvare z obojestranskim pnevmotoraksom in dihalne odpovedi. Naknadno smo pri izolirani bakteriji S. aureus s postopkom, ki ga opisujemo, dokazali prisotnost gena za PEI. Zaključki Pri bolniku z nekrotizirajočo pljučnico in septičnim šokom smo osamili PVL pozitivni S. aureus in S. pneumoniue. Da v prihodnosti preprečimo širjenje okužbe s PVL pozitivno bakterijo S. aureus, bi bili verjetno potrebniukrepi, kot jih poznamo za proti meticilinu odporni S. ctureus"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-DLZHATOQ","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-DLZHATOQ"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-DLZHATOQ/c1182ca7-0108-4a97-9ee1-e3f63f951ef2/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-DLZHATOQ/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-DLZHATOQ"}}}}