19 KB444 KB18 KB192920262012Bitenc, MarkoKern, IzidorZidarn, Mihaelaštevilka:1letnik:81str. 77-81ISSN:1318-0347COBISSID:29488857URN:URN:NBN:SI:doc-DQ3QGLEMslSlovensko zdravniško društvoZdravniški vestnikAdverse EffectsAgedAnafilaksijaAnaphylaxisAnestezija splošnaAnesthesia, GeneralFatal OutcomeSmrtni izidStarostnikiSuccinylcholineSukcinilholinFatalna anafilaktična reakcija med anestezijo| Fatal anaphylactic reaction during anesthesia|Background: Incidence of anaphylactic reactions occuring during anesthesia is not known. They occur most often in the induction phase and can present with different levels of severity, also as an anaphylactic shock. Neuromuscular blocking drugs are the most frequently involved substances. Case presentation:We report a case of a 77-year old female patient with granulomatous inflammation of unknown etiology. Surgical biopsy of a neck lymph node was indicated. During the induction of anesthesia using propofol and succinylcholine she developed severe anaphylactic reaction presented with bronchospasm and cardiac arrest. Despite 80 min continous cardiopulmonary resuscitation the patient died. Elevated tryptase level in the patientćs bloodsample taken before death confirmed anaphylactic reaction. On autopsy we confirmed the tuberculous etiology of generalized granulomatous inflammation. Conclusions: It is important to recognize anaphylactic reaction during anesthesia early and to take adequate measures in order to prevent unfavorableoutcome. Tryptase assay of a blood sample taken during life or postmortem may help to identify anaphylactic reactionTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo