31 KB74 KB12 KB192920262008Grat, MatejaJelenko, TadejaVučković, Joškoštevilka:13 straniletnik:77str. I-157-I-159ISSN:1318-0347COBISSID:24133849URN:URN:NBN:SI:doc-FGWS981TslSlovensko zdravniško društvoZdravniški vestnikdiagnostikahepatitisklinična slikalevkemijavirusni hepatitisFulminantni Epstein-Barr virusni hepatitis pri bolniku s kronično limfocitno levkemijo in okrnjeno imunsko odzivnostjo| Fulminant Epstein-Barr viral hepatitis in immunocompromised patient with chronic lymphocytic leukaemia|Backrgound Fulminant hepatitis with acute hepatic failure caused by Epstein-Barr virus (EBV) reactivation is rare and has high mortality. We report a case of fulminant EBV hepatitis with acute hepatic failure, disseminated intravascular coagulation and multiorgan failure in chronic lymphocytic leukaemia patient in relaps treated with alemtuzumab (monoclonal antiCD52) and standard chemoprophylaxis. After transient neutropenia he becameicteric and had upper abdominal pain. The course was progressive and he died 13 days after onset of symptoms. We confirmed serologically and moleculary (EBV-DNA PCR) reactivation of EBVTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo