12 KB155 KB11 KB199220252005Aksu, GörkemArslan, MehmetGüveli, MuratKaradeniz, Ahmet N.številka:1letnik:395 stranistr. 55-59ISSN:1318-2099COBISSID:19322073URN:URN:NBN:SI:doc-GLY9HHM7enAssociation of Radiology and OncologyRadiology and oncology (Ljubljana)DiagnosisglavakarcinomMiddle AgeNeoplasm InvasivenessNovotvorba, invazivnostParietal BoneParietalna kostPathologyrak (medicina)Srednja letaSurgerySweat Gland Neoplasmsznojne žlezeZnojnica, novotvorbeCranium eroding sweat carcinoma| a case report|Background. Sweat gland carcinomas are rare turnors. Eccrine sweat gland carcinomas are also very rare, with only about 200 cases reported in the worldliterature and only one of them was eroding the cranium. Treatment modalities of these carcinomas are not well known. Case report. Our patient was 47 years old female. Since 1989, she was operated on six times because o fthe tumour relapses. After each operation, the pathological results were: sweat gland adenoma, sweat gland tumour, cylindroma, turban tumour, malign cylindiroma. That was her seventh relapse. On examination, a lesion of the size 10 x 6 cm was observed in the left parietal region. Computed tomography showed the lesion had the size of 11 x 5 cm, and was destroying the tabula externa, diploic region and tabula. The tumour was invading the dura and causing periost reaction. Surgery and postoperative radiotherapy treatment wasplanned because of malign transformation and risk of recurrence. Conclusians. Only one case with cranium erosion was reported in literature. Inour case, also intracranial extension of the tumor was observedIzhodišča. Karcinomi znojnih žlez so redki tumorji. Prav tako so redki tisti karcinomi znojnih žlez, ki so žlezno aktivni. Do sedaj je v literaturi opisanih le okoli 200 primerov in samo eden je razjedal lobanjske kosti. Zaradi njihove redkosti tudi ne poznamo najprimernejšega in najučinkovitejšegazdravljenja. Prikaz primera. Opisujemo 47-letno bolnico, ki so jo po začetni operaciji leta 1989 še šestkrat operirali zaradi ponavljajočega se tumorja v predelu kože kraniuma. Patomorfološki pregled je po vsaki operaciji pokazal benigni tumor (adenom znojne žleze, cilindrom), razen po zadnji, ko smo ugotovili maligni cilindrom. Pred zadnjo operacijo smougotovili, da je recidivni tumor, ki je ležal v levi parietalni regiji velik 10 x 6 cm. Z računalniško tomografijo pa smo videli, da je 11 x 5 cm velik tumor poškodoval lobanjske kosti, vraščal v duro ter povzročal periostalno reakcijo. Zaradi maligne transformacije in velike nevarnosti ponovitve bolezni smo se odločili za postoperativno radioterapijo. Zaključki. Do sedaj je ob naši bolnici opisan samo še en primer, kjer je tumor znojnih žlez vraščal v lobanjske kostiTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo radiologije in onkologije