22 KB101 KB18 KB199220252006Ishikawa, HiroichiKagohashi, KatsunoriKurishima, KoichiOhtsuka, MorioSatoh, Hiroakištevilka:4letnik:407 stranistr. 239-244ISSN:1318-2099COBISSID:22455513URN:URN:NBN:SI:doc-H37FGTSGenAssociation of Radiology and OncologyRadiology and oncology (Ljubljana)AdenocarcinomaAdenokarcinomBody Mass IndexDejavniki tveganjaepidemiologijaEpidemiologyindeks telesne maseLung NeoplasmsPljučne novotvorbepljučni rakRisk Factorsrizični faktorjiTelesna masa, indeksBody mass index and lung cancer risk in never smokers|Background. A relationship between body mass index (BMI) and lung cancer risk in never smokers has not been reported precisely. To evaluate the risk of lungcancer associated with BMI in never smokers, we conducted a case-control study. Methods. The relationship between BMI and the risk of lung cancer in never smokers was investigated in a study of 204 lung cancer cases and 398 controls admitted between 1987 and 2005. Controls were selected from hospitalized age-matched never-smoking patients with non-malignant respiratorydisease. Results. When compared with BMI of the leanestgroup (BMI <20.8) in men, no inverse association between BMI and lung cancer was observedafter the adjustment for age (the second BMI group: BMI >= 20.8 to < 22.9; p = 0,683, the third BMI group: BMI >= 22.9 to < 24.9; p = 0.745, and the highest BMI group: BMI >= 25.0; p = 0.327). Similarly, no association in women was found between BMI and lung cancer in these three BMI groups (the second group, p = 0.639; the third group, p = 0.667; the highest group, p = 0.978) when compared with that of the leanest BMI group. Conclusions. Our present study indicated that the association between leanness and the risk of lung cancer might be influenced by other factors such as smokingIzhodišča. Razmerje med indeksom telesne mase (BMI) in tveganjem za pljučnega raka pri nekadilcih do sedaj še ni bilo natančno opredeljeno. Da bi to tveganje ocenili, smo naredili študijo primerov. Metode. V letih 1987 do 2005 smo v raziskavi obravnavali 204 bolnikov nekadilcev s pljučnim rakom in 398 bolnikov v kontrolni skupini. Starostno primerljive bolnike v kontrolni skupini smo izbrali med nekadilci, ki so se zdravili v naši bolnišnici zaradi nemaligne pljučne bolezni. Rezultati. Ko smo primerjali starostno primerljivo skupino bolnikov z najmanjšim BMI (BMI < 20.8), nismo ugotovili manjše povezave s pljučnim rakom kot v skupinah z višjim BMI (v drugi skupini z BMI >= 20,8 do < 22,9, p = 0,683; v tretji skupini z BMI >= 22,9 do < 24,9, p = 0,745; in v skupini z najvišjim BMI, BMI >= 25,0, p = 0,327). Prav tako primerjava omenjenih skupin pri ženskah ni pokazala povezave med BMI in pojavnostjo pljučnega raka (pri drugi skupini je bil p = 0,639; pri tretji p =0,667; in pri skupini z najvišjim BMI p = 0,978). Zaključki. Naša raziskava ni pokazala, da bi pri nekadilcih BMI bil povezan s stopnjo tveganja za pljučnega raka. Na obolevanje za pljučni rak še vedno najbolj vplivajo drugi dejavniki, največ kajenjeTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo radiologije in onkologije