732 KB0 KB199220252023Battista, MichelaBertino, GiuliaCampana, Luca GiovanniČemažar, MajaDe Terlizzi, FrancescaGrošelj, AlešKis, ErikaKrt, AljošaMcCafferty, IanMuir, TobianOdili, JoyOmerzel, MašaRatnam, LakshmiSerša, GregorWohlgemuth, Walter AZanasi, Alessandroštevilka:2letnik:57str. 141-149DOI:10.2478/raon-2023-0029ISSN:1318-2099COBISSID:159007235URN:URN:NBN:SI:doc-JOWZRV4OenCroatian Medical Association - Croatian Society of RadiologySlovenian Medical Society - Section of RadiologyRadiology and oncology (Ljubljana)bleomycinelectrosclerotherapyelektroskleroterapijavascular malformationsžilne malformacijeBleomycin electrosclerotherapy (BEST) for the treatment of vascular malformations| an International Network for Sharing Practices on Electrochemotherapy (InspECT) study group report|Biomedical applications of electroporation are expanding out of the field of oncology into vaccination, treatment of arrhythmias and now in the treatment of vascular malformations. Bleomycin is a widely used sclerosing agent in the treatment of various vascular malformations. The application of electric pulses in addition to bleomycin enhances the effectiveness of the drug, as demonstrated by electrochemotherapy, which utilizes bleomycin in the treatment of tumors. The same principle is used in bleomycin electrosclerotherapy (BEST). The approach seems to be effective in the treatment of low-flow (venous and lymphatic) and, potentially, even high-flow (arteriovenous) malformations. Although there are only a few published reports to date, the surgical community is interested, and an increasing number of centers are applying BEST in the treatment of vascular malformations. Within the International Network for Sharing Practices on Electrochemotherapy (InspECT) consortium, a dedicated working group has been constituted to develop standard operating procedures for BEST and foster clinical trials. By treatment standardization and successful completion of clinical trials demonstrating the effectiveness and safety of the approach, higher quality data and better clinical outcomes may be achievedTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo radiologije in onkologije