253 KB30 KB192920262004Čižek-Sajko, MojcaGavrić-Lovrec, VidaKovač, VilmaKovačič, BorutReljič, MilanVlaisavljević, Veljkoštevilka:4letnik:73str. 313-317ISSN:1318-0347COBISSID_HOST:1524031URN:URN:NBN:SI:doc-RK6RTEZKslSlovensko zdravniško društvoZdravniški vestnikFertilization in vitroInjiciranje semena, intracitoplazmičnoNosečnost, izidOploditev in vitroPregnancy rateReproductive techniques, assistedReproduktivne tehnike, asistiraneSperm injections, intracytoplasmicProgram zunajtelesne oploditve v Mariboru v petletnem obdobju 1998-2002| Programme of assisted reproduction in Maribor over the period 1998-2002|Background. During the period between 1998 and 2002 Department for reproductive medicine, Maribor Teaching Hospital performed 31.1% of all cycles of assisted reproduction (ART) in Slovenia. Methods. Three different methods of ART (in vitro fertilization - IVF, intracytoplasmic sperm injection with ejaculated sperm - ICSI and testicular sperm TESA/TESE) were compared. Comparison of clinical results was also made between the period when up to 4 embrios were transferred and the period when up to 2 embrios were transferred. Results. During the five year period, pregnancy rate per started cycle was between 29.6% in 1998 and 36.4% in 2002. During the whole period, delivery rate per started cycle was higher than the mean average reported for European centers for the year 1999. The observed values were higher with the tendeny to slightly increase from 27.4% in 1998 to 30.8% in 2001. Conclusions. Clinical results of ART programme at Maribor Clinic for reproductive medicine in the observed five year period over the period 1998-2002 were superior to the last results published by the European register of ARTIzhodišča. V obdobju med 1998 in 2002 je Oddelek za reproduktivno medicino Splošne bolnišnice v Mariboru opravil 31,1% vseh ciklusov oploditev z biomedicinsko pomoejo (OBMP) v Sloveniji. Metode. Primerjali smo uspešnost OBMP pri treh metodah zdravljenja (klasično zunajtelesno oploditev - IVF, injekcijo semenčice v citoplazmo jajčne celice z ejakulirano semenčico - ICSI in semenčico, pridobljeno z biopsijo testisa (TESA/TESE). Rezultati. V opazovanem petletnem obdobju je bila stopnja zanositev na začeti ciklus med 29,6% v letu 1998 in 36,4% v letu 2002. Stopnja porodov na začeti ciklus je bila v celotnem opazovanem obdobju višja kot je povprečna vrednost v zadnjem evropskem registru za leto 1999. Opazovane vrednosti so višje in kažejo tendenco k blagemu porastu od 27,4% v letu 1998 na 30,8% v letu 2001. Zaključki. Klinični rezultati programa OBMP na Oddelku za reproduktivno medicino Splošne bolnišnice v Mariboru so v opazovanem petletnem obdobju med 1998. in 2002. letom višji od povprečja, o katerem poroča evropski register za OBMPTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo