<?xml version="1.0"?><rdf:RDF xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:edm="http://www.europeana.eu/schemas/edm/" xmlns:wgs84_pos="http://www.w3.org/2003/01/geo/wgs84_pos" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:rdaGr2="http://rdvocab.info/ElementsGr2" xmlns:oai="http://www.openarchives.org/OAI/2.0/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:ore="http://www.openarchives.org/ore/terms/" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:dcterms="http://purl.org/dc/terms/"><edm:WebResource rdf:about="http://www.dlib.si/stream/URN:NBN:SI:doc-SC19IH7M/363735c1-9743-4097-9fcf-433a16f797b6/HTML"><dcterms:extent>24 KB</dcterms:extent></edm:WebResource><edm:WebResource rdf:about="http://www.dlib.si/stream/URN:NBN:SI:doc-SC19IH7M/0902fc60-f564-4df0-ac79-50513f552395/PDF"><dcterms:extent>83 KB</dcterms:extent></edm:WebResource><edm:WebResource rdf:about="http://www.dlib.si/stream/URN:NBN:SI:doc-SC19IH7M/7fc10260-f886-440e-9b14-292bec68962d/TEXT"><dcterms:extent>22 KB</dcterms:extent></edm:WebResource><edm:TimeSpan rdf:about="1929-2026"><edm:begin xml:lang="en">1929</edm:begin><edm:end xml:lang="en">2026</edm:end></edm:TimeSpan><edm:ProvidedCHO rdf:about="URN:NBN:SI:doc-SC19IH7M"><dcterms:isPartOf rdf:resource="https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp" /><dcterms:issued>2009</dcterms:issued><dc:creator>Arko, Darja</dc:creator><dc:format xml:lang="sl">številka:1</dc:format><dc:format xml:lang="sl">letnik:78</dc:format><dc:format xml:lang="sl">str. I-201-I-205</dc:format><dc:identifier>ISSN:1318-0347</dc:identifier><dc:identifier>COBISSID:3486015</dc:identifier><dc:identifier>URN:URN:NBN:SI:doc-SC19IH7M</dc:identifier><dc:language>sl</dc:language><dc:publisher xml:lang="sl">Slovensko zdravniško društvo</dc:publisher><dcterms:isPartOf xml:lang="sl">Zdravniški vestnik</dcterms:isPartOf><dc:subject xml:lang="en">breast</dc:subject><dc:subject xml:lang="en">Breast Neoplasms</dc:subject><dc:subject xml:lang="sl">Dojka, novotvorbe</dc:subject><dc:subject xml:lang="sl">dojke</dc:subject><dc:subject xml:lang="sl">Kakovost življenja</dc:subject><dc:subject xml:lang="sl">klimakterij</dc:subject><dc:subject xml:lang="en">Menopause</dc:subject><dc:subject xml:lang="sl">Menopavza</dc:subject><dc:subject xml:lang="en">Quality of Life</dc:subject><dc:subject xml:lang="sl">rak (medicina)</dc:subject><dc:subject xml:lang="en">standard of living</dc:subject><dc:subject xml:lang="en">therapy</dc:subject><dc:subject xml:lang="en">Vaginitis</dc:subject><dc:subject xml:lang="sl">Zdravljenje</dc:subject><dcterms:temporal rdf:resource="1929-2026" /><dc:title xml:lang="sl">Možnosti zdravljenja klimakteričnih težav pri bolnicah z rakom dojk| Treatment possibilities of menopausal symptoms in breast cancer patients|</dc:title><dc:description xml:lang="sl">Background. Breast cancer is the most common cancer in women. Menopausal symptoms, which can highly reduce quality of life in women of all ages, are frequent side-effects of systemic treatment of early breast cancer whether treated by hormonal or cytotoxic therapy. Methods. The article presents literature review of the causes, assessment and management of menopausal syptoms in breast cancer patients. Results. There are a number of non-hormonal drugs effective in treating vasomotor symptoms, and some alternative therapies, such as black cohosh, phytoestrogens, homeopathy, acupuncture, yoga and behaviour strategies. The decision, whether and which pharmacologic or non-pharmacologic treatment to choose, depends on symptoms and on patient wishes. The most effective drugs for reducing hot flashes are vanlafaxine, paroxetine and gabapentin, unfortunately, the side effects are common. Vaginal estrogens are the most effective for treating atrophic vaginitis, but the safety in breast cancer patients is no established. Conclusions. Menopausal symptoms after breast cancer are severe and frequent and significantly reduce quality of life. Unfortunately, the possibility of treatment is limited</dc:description><dc:description xml:lang="sl">Izhodišča. Rak dojk je najpogostejši rak pri ženskah. Klimakterične težave, ki zelo poslabšajo kakovost življenja pri ženskah vseh starosti, so pogost sopojav sistemskega zdravljenja, tako hormonskega zdravljenja kot zdravljenja s citostatiki. Metode. V prispevku je predstavljen pregled literature o vzrokih, načinu obravnave in možnostih zdravljenja klimakteričnih težav pri bolnicah z rakom dojk. Rezultati. Za lajšanje vazomotornih simptomov obstaja več vrst nehormonskih zdravil in nekaj alternativnih zdravljenj, na primer z rastlino cimicifugo, fitoestrogeni, homeopatijo, akupunkturo, jogo in spremembo načina življenja. Za kakšno vrsto farmakološkega ali nefarmakološkega zdravljenja se bomo odločili, zavisi od vrste težav ter želja bolnice. Najbolj učinkovita zdravila za zmanjšanje vročinskih oblivov so venlafaksin, paroksetin in gabapentin, žal pa so sopojavi pogosti. Za lajšanje težav zaradi atrofičnega kolpitisa so najbolj učinkoviti lokalno aplicirani estrogeni, vendar varnost pri bolnicah z rakom dojk ni povsem dognana. Zaključki. Klimakterične težave pri bolnicah z rakom dojk so pogost in resen problem, ki bistveno vpliva na kakovost življenja. Možnosti zdravljenja so na žalost precej omejene</dc:description><edm:type>TEXT</edm:type><dc:type xml:lang="sl">znanstveno časopisje</dc:type><dc:type xml:lang="en">journals</dc:type><dc:type rdf:resource="http://www.wikidata.org/entity/Q361785" /></edm:ProvidedCHO><ore:Aggregation rdf:about="http://www.dlib.si/?URN=URN:NBN:SI:doc-SC19IH7M"><edm:aggregatedCHO rdf:resource="URN:NBN:SI:doc-SC19IH7M" /><edm:isShownBy rdf:resource="http://www.dlib.si/stream/URN:NBN:SI:doc-SC19IH7M/0902fc60-f564-4df0-ac79-50513f552395/PDF" /><edm:rights rdf:resource="http://creativecommons.org/licenses/by-nc/4.0/" /><edm:provider>Slovenian National E-content Aggregator</edm:provider><edm:intermediateProvider xml:lang="en">National and University Library of Slovenia</edm:intermediateProvider><edm:dataProvider xml:lang="sl">Slovensko zdravniško društvo</edm:dataProvider><edm:object rdf:resource="http://www.dlib.si/streamdb/URN:NBN:SI:doc-SC19IH7M/maxi/edm" /><edm:isShownAt rdf:resource="http://www.dlib.si/details/URN:NBN:SI:doc-SC19IH7M" /></ore:Aggregation></rdf:RDF>