210 KB0 KB192920262018Brvar, MiranLeben, Laraštevilka:5/6letnik:87str. 297-303ISSN:1318-0347COBISSID:34141913URN:URN:NBN:SI:doc-SC2JNSEZslSlovensko zdravniško društvoZdravniški vestnikguaranakofeinpoživilapredoziranjezastrupitveZastrupitev z guarano| Acute guarana poisoning| prikaz dveh primerov| report of two cases|Guarana ( Paullinia cupana ) is a South American plant that contains twice more caffeine com - pared to coffee beans, and has a stimulatory effect. Thus guarana preparations in the form of capsules, tablets, powders, teas, syrups and energy drinks contain a lot of caffeine, which can rapidly cause poisoning even when only slightly overdosed. Caffeine poisoning may result in irritability, insomnia, anxiety, restlessness, muscle twitching, nausea or vomiting, rapid heart beat or cardiac arrhythmias, high blood pressure, sweating, diuresis and gastroinestinal disturbance. This report presents two cases of guarana overdose with the common caffeine poisoning symp - toms and signs. Guarana in therapeutic doses can exacerbate underlying cardiac disease (espe - cially cardiac arrhythmias, coronary heart disease, heart failure) and diabetes. Furthermore, children, pregnant and nursing women should avoid guarana as well. Treatment of guarana poisoning is symptomatic, mainly with benzodiazepines and by fluid and electrolyte substitutionTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo