557 KB0 KB199220252023Birk, MojcaHertl, KristijanaJarm, KatjaKlaneček, ŽanKrajc, MatejaStuden, AndrejŠval, CvetoVrhovec, MilošZadnik, Vesnaštevilka:3letnik:57str. 337-347DOI:10.2478/raon-2023-0039ISSN:1318-2099COBISSID:167515651URN:URN:NBN:SI:doc-SCFPCVC8enCroatian Medical Association - Croatian Society of RadiologySlovenian Medical Society - Section of RadiologyRadiology and oncology (Ljubljana)breast cancer screeningdejavniki tveganjamammographymamografijapersonalised screeningpersonalizirano presejanjepresejalni programirak dojkerisk assessmentBreast cancer risk assessment and risk distribution in 3,491 Slovenian women invited for screening at the age of 50| a population-based cross-sectional study|Background. The evidence shows that risk-based strategy could be implemented to avoid unnecessary harm in mammography screening for breast cancer (BC) using age-only criterium. Our study aimed at identifying the uptake of Slovenian women to the BC risk assessment invitation and assessing the number of screening mammographies in case of risk-based screening.Patients and methods. A cross-sectional population-based study enrolled 11,898 women at the age of 50, invited to BC screening. The data on BC risk factors, including breast density from the first 3,491 study responders was col-lected and BC risk was assessed using the Tyrer-Cuzick algorithm (version 8) to classify women into risk groups (low, population, moderately increased, and high risk group). The number of screening mammographies according to risk stratification was simulated. Results. 57% (6,785) of women returned BC risk questionnaires. When stratifying 3,491 women into risk groups, 34.0% were assessed with low, 62.2% with population, 3.4% with moderately increased, and 0.4% with high 10-year BC risk. In the case of potential personalised screening, the number of screening mammographies would drop by 38.6% com-pared to the current screening policy. Conclusions. The study uptake showed the feasibility of risk assessment when inviting women to regular BC screen-ing. 3.8% of Slovenian women were recognised with higher than population 10-year BC risk. According to Slovenian BC guidelines they may be screened more often. Overall, personalised screening would decrease the number of screening mammographies in Slovenia. This information is to be considered when planning the pilot and assessing the feasibility of implementing population risk-based screeningTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo radiologije in onkologije