{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-T781W3OS/5bc466c8-f3a0-463b-b50d-e2c17c1ca56d/HTML","dcterms:extent":"28 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-T781W3OS/6692c647-6b67-4d47-8cef-77bc029afec0/PDF","dcterms:extent":"137 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-T781W3OS/3a76dc5a-adae-46bd-84d7-4c1733dbe884/TEXT","dcterms:extent":"23 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-T781W3OS","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2003","dc:creator":["Battelino, Tadej","Berce, Vojko","Bratanič, Nevenka","Bratina, Nataša","Kržišnik, Ciril","Saje-Hribar, Nada","Žerjav-Tanšek, Mojca"],"dc:format":[{"@xml:lang":"sl","#text":"številka:1"},{"@xml:lang":"sl","#text":"letnik:72"},{"@xml:lang":"sl","#text":"str. 7-10"}],"dc:identifier":["ISSN:1318-0347","COBISSID:15979225","URN:URN:NBN:SI:doc-T781W3OS"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"en","#text":"Blood"},{"@xml:lang":"en","#text":"Body Mass Index"},{"@xml:lang":"en","#text":"cardiovascular disease"},{"@xml:lang":"en","#text":"child"},{"@xml:lang":"en","#text":"Child, Preschool"},{"@xml:lang":"en","#text":"Cholesterol"},{"@xml:lang":"sl","#text":"Holesterol"},{"@xml:lang":"sl","#text":"kardiovaskularne bolezni"},{"@xml:lang":"en","#text":"Mass Screening"},{"@xml:lang":"sl","#text":"Množični pregledi"},{"@xml:lang":"sl","#text":"otroci"},{"@xml:lang":"sl","#text":"Otrok predšolski"},{"@xml:lang":"en","#text":"Sex Factors"},{"@xml:lang":"sl","#text":"Spolni faktorji"},{"@xml:lang":"sl","#text":"Telesna masa, indeks"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Presejalno določanje holesterola pri pet let starih otrocih v Sloveniji| Screening for hypercholesterolemia in 5 year old children in Slovenia|"},"dc:description":[{"@xml:lang":"sl","#text":"Background. Cardiovascular diseases represent the most frequent cause of morbidity and mortality in developed countries. Blood cholesterol concentration inffluences the progression of atherosclerosis and most developed countries started programs for early detection of hypercholesterolemia. The study presents data analysis related to the total cholesterol concentrations obtained from 5-year old children. Additionally, guidelines for improving the follow-up work with children having hypercholesterolemia are presented. Methods. Values of total cholesterol concentration of 2742 children born 1995 or 1996 were obtained from 17 pediatric primary care facilities in Slovenia. Data analysis included values of body mass index (BMI). The study was approved by the State Committee for Medical Ethics (103/02/02). Results. Values of total cholesterol concentrationwere not distributed according to the normal distribution. Total cholesterol concentration was significantly higher in girls (median 4.41 mmol/L, 5th percentile 3.3 mmol/l and 95th percentile 5.8 mmol/L) compared to boys (median 4.3 mmol/L, 5th percentile 3.2 mmol/l and 95th percentile 5.6 mmol/L) (p < 0.0001). Twenty-one percent of values were above 5 mmol/L, 15% above 5.2 mmol/L and 2.8% above 6 mmol/L. Total cholesterol concentration did not correlate with the BMl. (Abstract truncated at 2000 characters)"},{"@xml:lang":"sl","#text":"Izhodišča. Bolezni srca in ožilja predstavljajo v razvitem svetu najpogostejšivzrok zbolevnosti in smrtnosti. Razvoj ateroskleroze, ki je vzroktem boleznim, je močno odvisen od koncentracije holesterola v krvi. Večina razvitih držav zato uvaja zgodnje presejalno testiranje za odkrivanje hiperholesterolemije. V naši raziskavi smo analizirali podatke, dobljene pri slovenskem presejalnem testiranju petletnih otrok ob sistematskem pregledu in na podlagi naših in tujih izkušenj izoblikovali smernice za obravnavo otrok inmladostnikov s hiperholesterolemijo. Metode. Analizirali smo vrednosti koncentracije celokupnega holesterola 2742 naključno izbranih 5-letnih otrok, rojenih leta 1995 in 1996, iz 17 pediatričnih dispanzerjev po Sloveniji. V statistično analizo je bil zajet tudi indeks telesne mase (ITM). Raziskavo je odobrila Komisija za medicinsko etiko (103/02/02). Rezultati. Vrednosti koncentracije celokupnega holesterola niso razporejene skladno z normalno razporeditvijo. Koncentracija celokupnega holesterola je značilno višja pri deklicah (mediana 4,41 mmol/L, 5 percentila 3,,3 mmol/l, 95 percentila 5,8 mmol/L) kot pri dečkih (mediana 4,3 mmol/L, 5 percentila 3,2 mmol/l, 95 percentila 5, 6 mmol/L) (p < 0,0001). Enaindvajset odstotkov vrednosti je nad 5 mmol/L, 15 % nad 5,2 mmol/L in 2,8% nad 6 mmol/L. Vrednosti koncentracije celokupnega holesterola ne korelirajo z vrednostmi ITM. (Izvleček skrajšan pri2000 znakih)"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-T781W3OS","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-T781W3OS"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-T781W3OS/6692c647-6b67-4d47-8cef-77bc029afec0/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-T781W3OS/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-T781W3OS"}}}}