18 KB134 KB17 KB192920262003Benkovič, AlenkaHorvat, MatejaKološa, IvanaKovačič, SrečkoLopert, AntonPetric, VlastaVolavšek, Metkaštevilka:5letnik:72str. 271-273COBISSID:1208383ISSN:1318-0347URN:URN:NBN:SI:doc-VMO38F2EslSlovensko zdravniško društvoZdravniški vestnikCelice ubijalke, naravneEndomyocardial fibrosisEosinophiliaEozinofilijaFibroza endomiokardaheartKiller cells, naturallimfomLimfom, T-celiceLymphoma, T-cellsrcesrčne bolezniEozinofilija pri bolniku z ekstranodalnim limfomom T naravnih ubijalk| A case of extranodal NK/T cell lymphoma presenting with eosinophilia| prikaz primera|Background. Eosinophilia can occur in extranodal NK/T cell lymphoma. Chronic hypereosinophilia from any cause is associated with endomyocardial fibrosis. Methods and material. This report includes on a patient with hypereosinophilia which was diagnosed and investigated nine months before the diagnosis of extranodal NK/T cell lymphoma (nasal type) of the larynx was confirmed by biopsy. He died with signs of heart failure 11 months after the first symptoms developed. Post mortem investigation revealed endomyocardial fibrosis as a result of chronic hypereosinophilia. Conclusions. To our knowledge eosinophilia has not previously been reported in extranodal NK/T cell lymphoma (nasal type). Therefore, this is considered to be a rare feature of the presented case. Investigation of the heart for potential silent complications of prolonged and severe eosinophilia has to be considered at an early stageIzhodišča. Eozinofilija se lahko pojavi tudi pri ekstranodalnem limfomu T naravnih ubijalk (T/NU). Če je dolgotrajna, lahko vodi v okvaro srčne mišice. Bolniki in metode. Prikazujemo primer bolnika z eozinofilijo, ugotovljeno devet mesecev pred postavitvijo diagnoze ekstranodalnega limfoma T/NU grla. Bolnik je umrl zaradi srčne odpovedi 11 mesecev po prvih simptomih. Na obdukciji je bila ugotovljena fibroza endomiokarda kot posledica kronične eozinofilije. Zaključki. Eozinofilija pri ekstranodalnem limfomu T/NU še ni bila opisana, zato menimo, da gre za redek primer. Pri bolnikih z izrazito eozinofilijo je pomembno zgodnje odkrivanje okvare srca, ki je lahko asimptomatskaTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo