{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-XGZCLUNC/c07ca8d2-13c1-45ae-97b4-9a1e72a52ad3/HTML","dcterms:extent":"32 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-XGZCLUNC/388d6d99-981a-4d44-9d8b-a3afdb1f1c95/PDF","dcterms:extent":"74 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-XGZCLUNC/222eb604-bc58-44f2-b3c6-d3b9413982eb/TEXT","dcterms:extent":"16 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-XGZCLUNC","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-FNIFVE9S"},{"@xml:lang":"sl","#text":"Radiology and oncology (Ljubljana)"}],"dcterms:issued":"2005","dc:creator":["Serin, Meltem","Şükrü Erkal, Haldun"],"dc:format":[{"@xml:lang":"sl","#text":"letnik:39"},{"@xml:lang":"sl","#text":"številka:4"},{"@xml:lang":"sl","#text":"5 strani"},{"@xml:lang":"sl","#text":"str. 273-277"}],"dc:identifier":["ISSN:1318-2099","COBISSID:20668633","URN:URN:NBN:SI:doc-XGZCLUNC"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Association of Radiology and Oncology"},"dc:subject":[{"@xml:lang":"sl","#text":"novotvorbe"},{"@xml:lang":"sl","#text":"prostata"},{"@xml:lang":"sl","#text":"Prostata, novotvorbe"},{"@xml:lang":"en","#text":"prostate"},{"@xml:lang":"en","#text":"Prostatic Neoplasms"},{"@xml:lang":"sl","#text":"radioterapija"},{"@xml:lang":"sl","#text":"Radioterapija, doziranje"},{"@xml:lang":"en","#text":"Radiotherapy"},{"@xml:lang":"en","#text":"Radiotherapy Dosage"},{"@xml:lang":"sl","#text":"rak (medicina)"},{"@xml:lang":"en","#text":"tumor"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Correlation of clinical target volume and the margins to define planning target volume with beam arrangements for three-dimensional conformal radiation therapy delivery for prostate cancer|"},"dc:description":[{"@xml:lang":"sl","#text":"Background. A conceptual study was undertaken to correlate the clinical targetvolume and the margins to define the planning target volume with the beam arrangements for a three-dimensional conformal radiation therapy deliveryon two patients with prostate cancer having considerably different prostate shapes and volumes. Material and methods. The clinical target volume was defined as prostate and seminal vesicles. Uniform margins of 0.4, 0.8 and 1.2 cm were added around the clinical target volume to define three planning target volumes. Three well-established coplanar beam arrangements were simulated for all planning target volumes. Dose-volume histograms were calculated and quantitatively compared. Results. The mean dose (Dm) for PTVs ranged from 98.7 to 99.9%, with standard deviations ranging from 1.5 to 1.7%. Plan I appeared to be the best considering the Dm for the rectum, whereas PlanII appeared to be the best considering V95 (fraction of volume receiving adose higher than 95% of the isocenter dose for the rectum). Plan III appearedto be the best considering the Dm and V95 for the bladder and also considering the Dm and V50 for the femur. Conclusions. This conceptual study suggested that the differences in shapes and volumes of planning target volumemight be taken into consideration in an attempt to individually establish the optimum beam arrangements for three-dimensional conformal radiation therapy delivery in prostate cancer"},{"@xml:lang":"sl","#text":"Izhodišča. Primerjalna študija je bila opravljena na dveh bolnikih z rakom prostate različnih oblik in volumnov. Želeli smo ugotoviti razmerje med kliničnim tarčnim volumnom in varnostnim robom, ki določata planirni tarčni volumen (PTV) ter obliko polj pri tridimenzionalni konformni radioterapiji. Material in metode. Klinični tarčni volumen je vključeval prostato in seminalne vezikule. Varnostne robove dolžin 0,4 cm, 0,8 cm in 1,2 cm smo enakomerno dodali na klinični tarčni volumen in tako določili tri PTV. Pri vseh PTV smo simulirali tri dobro osnovana istoravninska (koplanarna) polja. Naredili smo histograme, ki so kazali razmerje med dozo in volumnom ter jih med seboj kvantitativno primerjali. Rezultati. Povprečna doza za PTV je bila vrazponu od 98,7 do 99,9%, s standardno deviacijo med 1,5 in 1,7%. Plan I je bil najboljši glede na povprečno dozo sevanja, ki ga je prejel rektum, medtem ko je bil Plan II najboljši glede na V95 za rektum (delež volumna, ki prejme dozo višjo od 95% doze določene v izocentru). Plan III je bil najboljši tako glede na povprečno dozo sevanja in V95 za mehur kot tudi glede na povprečno dozo sevanja in V50 za glavice kolkov. Zaključki. Primerjalna študija kaže, damoramo upoštevati razlike v oblikah in volumnih planirnih tarčnih volumnov. Takšen pristop nam omogoča individualno določevanje optimalnih polj potrebnih za tridimenzionalno konformno radioterapijo v primeru raka prostate"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-XGZCLUNC","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-XGZCLUNC"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-XGZCLUNC/388d6d99-981a-4d44-9d8b-a3afdb1f1c95/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Društvo radiologije in onkologije"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-XGZCLUNC/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-XGZCLUNC"}}}}