{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-YVDN0LPH/8e04bb03-37ed-416a-97b3-dd7c81a4a91e/HTML","dcterms:extent":"43 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-YVDN0LPH/a14e023b-695b-460e-81bc-392274e9ec9b/PDF","dcterms:extent":"89 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-YVDN0LPH/fc838cf2-cefe-4182-9ce2-0081cc1b0166/TEXT","dcterms:extent":"41 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-YVDN0LPH","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2006","dc:creator":["Poredoš, Pavel","Poredoš, Peter","Visnovič-Poredoš, Aleksandra"],"dc:format":[{"@xml:lang":"sl","#text":"letnik:75"},{"@xml:lang":"sl","#text":"številka:8"},{"@xml:lang":"sl","#text":"str. 475-481"}],"dc:identifier":["ISSN:1318-0347","COBISSID:21557977","URN:URN:NBN:SI:doc-YVDN0LPH"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"ateroskleroza"},{"@xml:lang":"en","#text":"Atherosclerosis"},{"@xml:lang":"en","#text":"Blood Pressure"},{"@xml:lang":"en","#text":"Brachial Artery"},{"@xml:lang":"sl","#text":"Brahialna arterija"},{"@xml:lang":"en","#text":"Calcinosis"},{"@xml:lang":"en","#text":"Carotid Arteries"},{"@xml:lang":"sl","#text":"Dejavniki tveganja"},{"@xml:lang":"en","#text":"Diagnosis"},{"@xml:lang":"en","#text":"diagnostika"},{"@xml:lang":"sl","#text":"Endotelij žilni"},{"@xml:lang":"en","#text":"Endothelium, Vascular"},{"@xml:lang":"sl","#text":"Kalcinoza"},{"@xml:lang":"sl","#text":"Karotidne arterije"},{"@xml:lang":"sl","#text":"Krvni pritisk"},{"@xml:lang":"en","#text":"Pathology"},{"@xml:lang":"en","#text":"Risk Factors"},{"@xml:lang":"en","#text":"Tunica Intima"},{"@xml:lang":"en","#text":"Tunica Media"},{"@xml:lang":"sl","#text":"Tunika intima"},{"@xml:lang":"sl","#text":"Tunika medija"},{"@xml:lang":"en","#text":"Ultrasonography"},{"@xml:lang":"en","#text":"Vascular Diseases"},{"@xml:lang":"sl","#text":"Žilne bolezni"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Pomen odkrivanja predkliničnih oblik ateroskleroze| The significance of detection of preclinical atherosclerosis|"},"dc:description":[{"@xml:lang":"sl","#text":"Background Atherosclerosis is a chronic disease, which can go on for many decades with no clinically noticable changes. When clinical symptoms appear, the disease has usually already significantly progressed. There is currently no effective treatment for atherosclerosis. The disease can only be prevented.This is why it is important to detect it in its early stages, when preventive measures are the most effective. Today, with a help of non-invasiveinvest tion methods, mostly ultrasound based, we can detect changes in the structure and fu tion of artery wall, which are typical for theearly stages of atherosclerosis or predict disease course. Conclusions Suchchanges are: lower capability of artery expansion during an increased blood flow (endothelial dysfunction), intima-media thickening, artery walls, artery calcination and ankle-brachial index decrease. The research showed thatthese symptoms of preclinical atherosclerosis are tightly connected to authenticity of the risk factors, their number and duration, and that there isa tight connection between the general cardiovascular danger and the manifestation of preclinical and morphological changes of an artery wall. (Abstract truncated at 2000 characters)"},{"@xml:lang":"sl","#text":"Izhodišča Ateroskleroza je kronična bolezen, ki več let ali desetletij poteka brez klinično zaznavnih sprememb. Ob pojavu kliničnih znakov je bolezen običajno že močno napredovala. Zaenkrat še ne poznamo učinkovitega zdravljenjaateroskleroze. Bolezen lahko le preprečujemo. Zato je pomembno, da jo odkrijemo v najzgodnejšem obdobju, ko so preventivni ukrepi najučinkovitejši. Danes lahko s pomočjo neinvazivnih preiskavnih metod, zlastiultrazvočnih, odkrivamo spremembe v sestavi in delovanju arterijske stene, ki so značilne za zgodnje obdobje ateroskleroze, ali pa napovedujejo njen razvoj. Med takšne spremembe sodijo: zmanjšana sposobnost razširitve arterije med povečanjem krvnega obtoka (endotelna disfunkcija), zadebelitev intime in medije arterijske stene, kalcinacije arterij in zmanjšanje gleženjskega indeksa. (Izvleček skrajšan na 2000 znakov)"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-YVDN0LPH","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-YVDN0LPH"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-YVDN0LPH/a14e023b-695b-460e-81bc-392274e9ec9b/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-YVDN0LPH/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-YVDN0LPH"}}}}