{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-Z88ZSK0E/fbd7f576-6b0b-4edd-832e-1be271eb63d2/HTML","dcterms:extent":"13 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-Z88ZSK0E/55028a0b-a480-4949-ba03-f84e9cd5e8d4/PDF","dcterms:extent":"412 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-Z88ZSK0E/57eade0c-7cad-48f4-96c9-ea9cf98956ab/TEXT","dcterms:extent":"11 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-Z88ZSK0E","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-FNIFVE9S"},{"@xml:lang":"sl","#text":"Radiology and oncology (Ljubljana)"}],"dcterms:issued":"2003","dc:creator":["Georgievska-Kuzmanovska, Sonja","Janevik-Ivanovska, Emilija","Kovkarova, Elizabeta","Naumovski, John","Simova, Nina"],"dc:format":[{"@xml:lang":"sl","#text":"številka:1"},{"@xml:lang":"sl","#text":"letnik:37"},{"@xml:lang":"sl","#text":"4 strani"},{"@xml:lang":"sl","#text":"str. 9-12"}],"dc:identifier":["ISSN:1318-2099","COBISSID:16231641","URN:URN:NBN:SI:doc-Z88ZSK0E"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Association of Radiology and Oncology"},"dc:subject":[{"@xml:lang":"en","#text":"diagnostika"},{"@xml:lang":"en","#text":"Endoscopy, Gastrointestinal"},{"@xml:lang":"sl","#text":"Endoskopija gastrointestinalna"},{"@xml:lang":"en","#text":"Isotope Labeling"},{"@xml:lang":"sl","#text":"Izotopi, označevanje"},{"@xml:lang":"sl","#text":"Napovedna vrednost testov"},{"@xml:lang":"sl","#text":"Občutljivost in specifičnost"},{"@xml:lang":"en","#text":"Peptic Ulcer"},{"@xml:lang":"sl","#text":"Peptični ulkus"},{"@xml:lang":"en","#text":"Predictive Value Of Tests"},{"@xml:lang":"en","#text":"Radionuclide Imaging"},{"@xml:lang":"sl","#text":"scintigrafija"},{"@xml:lang":"en","#text":"Sensitivity And Specificity"},{"@xml:lang":"en","#text":"Sucralfate"},{"@xml:lang":"sl","#text":"Sukralfat"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Scintigraphic detection of peptic lesions with the method of radiolabelled sucralfate|"},"dc:description":[{"@xml:lang":"sl","#text":"Background. Sucralfate is an antiulcer agent that after peroral application strongly adheres to mucosal defects and in that way provides a protective barrier to further damage from acid and pepsin. If radiolabelled with a gamma isotope, it could be detected under a gamma camera pointing lesions to which it adhered. With the aim to confirm a suitable noninvasive method for investigation of caustic lesians of the upper gastrointestinal tract we evaluated in a preliminary study the validity of the radiolabelled sucralfate scintigraphy in detection of peptic disease. Patients and methods. With that purpose, 35 patients after an endoscopic examination underwent scintigraphy with Tc-99m-DTPA sucralfate. Patients were divided in two groups: a group of 20 patients with endoscopic confirmed peptic disease and a control group of 15persons who had not any disease of the upper gastrointestinal tract. Results. Lising the test for clinical evaluation of a new method, the scan showed sensitivity of 75%, specificity of 100% and accuracy of 85,7%. Conclusions. Scintigraphy with Tc-99m-DTPA sucralfate promoting it as an additional method, complementary to routine investigations in detecting mucosal lesions"},{"@xml:lang":"sl","#text":"Izhodišča. Sukralfat uporabljamo za zdravljenje ulkusne bolezni. Po peroralni aplikaciji se močno veže na poškodovano sluznico in na ta način zaščiti sluznico pred nadaljnjo poškodbo s kislino in pepsinom. Če sukralfat označimo z radioizotopom, ki je sevalec gama žarkov, lahko z gama kamero zaznamo morebitno poškodbo sluznice. Tako je bil namen študije potrditi primerno neinvazivno metodo za ugotavljanje razjede sluznice zgornjega gastrointestinalnega trakta. V preliminarni študiji smo ocenili pomen scintigrafije s sukralfatom, ki smo ga označili z radioizotopom, pri ugotavljanju peptične razjede. Bolniki in metode. Pri 35 bolnikih, ki so bili predhodno endoskopsko pregledani, smo naredili scintigrafijo s Tc-99m-DTPA sukralfatom. Bolniki so bili razdeljeni v 2 skupini: 20 jih je imelo endoskopsko potrjeno peptično razjedo, kontrolna skupina 15 bolnikov pa ni imela bolezni v zgornjem gastrointestinalnem traktu. Rezultati. Pri uporabi nove klinične metode smo ugotovili, da je imela scintigrafija 75 % senzitivnosti in 100 % specifičnosti ter 85,7% natančnosti. Zaključki. Scintigrafija s Tc-99m-DTPA sukralfatom lahko predstavlja dodatno dopolnjujočometodo pri rutinskem ugotavljanju sluzničnih razjed"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-Z88ZSK0E","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-Z88ZSK0E"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-Z88ZSK0E/55028a0b-a480-4949-ba03-f84e9cd5e8d4/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Društvo radiologije in onkologije"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-Z88ZSK0E/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-Z88ZSK0E"}}}}