{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-ZYCV7PXN/8e1ef732-90d2-4828-aa63-211b05c7adc1/HTML","dcterms:extent":"32 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-ZYCV7PXN/277e10be-c49e-4168-bb78-54d27be1c5bf/PDF","dcterms:extent":"79 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-ZYCV7PXN/b98b40f0-f63d-4e4e-816c-498e982d337c/TEXT","dcterms:extent":"30 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-ZYCV7PXN","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2003","dc:creator":"Marin, Jožica","dc:format":[{"@xml:lang":"sl","#text":"številka:2"},{"@xml:lang":"sl","#text":"letnik:72"},{"@xml:lang":"sl","#text":"str. 91-95"}],"dc:identifier":["ISSN:1318-0347","COBISSID:15957721","URN:URN:NBN:SI:doc-ZYCV7PXN"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"en","#text":"diagnostika"},{"@xml:lang":"sl","#text":"Eksantem subitni"},{"@xml:lang":"en","#text":"Exanthema Subitum"},{"@xml:lang":"sl","#text":"herpes virusi"},{"@xml:lang":"sl","#text":"Herpesvirus 6 človeški"},{"@xml:lang":"en","#text":"Herpesvirus 6, Human"},{"@xml:lang":"en","#text":"Roseolovirus Infections"},{"@xml:lang":"sl","#text":"Rozeolovirusne infekcije"},{"@xml:lang":"en","#text":"therapy"},{"@xml:lang":"en","#text":"virus"},{"@xml:lang":"sl","#text":"virusi"},{"@xml:lang":"sl","#text":"zdravljenje"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Človeški herpesvirus 6| Human herpesvirus 6|"},"dc:description":[{"@xml:lang":"sl","#text":"Background. Human herpesvirus 6 belongs to betaherpesviruses. This is a lymphotropic virus which is widely spread in a population. The most frequent way of virus transmission is by saliva. For this reason the first contact usally occurs early in a childhood period. Clinical manifestation might be expressed as exanthem subitum or roseola infantum. In adults primary infections are a rare event while virus reactivation might be very frequent. Conclusions. Human herpesvirus 6 is believed to be the most neurotropic among all herpesviruses. It even can cause central nervous system disease in an immunocompetent person. The most important role of human herpesvirus 6 is in provoking complications in HIV-infected individuals and in patients after organ transplantations, as it causes immunosupression even more severe. The possible connection of human herpesvirus 6 with multiple sclerosis, chronic fatigue syndrome and some neoplasmas remains to be clarified. Human herpesvirus 6 infection can be most easily diagnosed by serological methods; the virus could be detected by monoclonal antibodies and by the use of the methods of molecular biology"},{"@xml:lang":"sl","#text":"Izhodišča. Človeški herpesvirus 6 spada med betaherpesviruse. Je limfotropni virus, ki je zelo razširjen. Najpogostejši način prenosa je s slino. Zato do prvih stikov z virusom navadno pride že v zgodnjem otroštvu. Klinično se okužba lahko izrazi kot značilen izpuščaj - exanthem subitum ali roseola infantum. Pri odraslih so primarne okužbe redke, zelo pogosto pa se virus reaktivira. Zaključki. Človeški herpesvirus 6 lahko poškoduje osrednji živčni sistem. Celo pri imunsko normalno odzivnih posameznikih lahko povzroča meningoencefalitis in druge bolezni. Virus ima pomembno vlogo pri osebah, okuženih s HIV, in pri bolnikih po presaditvi organov. Povzroča zaplete, ker prispeva k še večji imunski pomanjkljivosti. Možnih povezav med človeškim herpesvirusom 6 in multiplo sklerozo, sindromom kronične utrujenosti in nastankom novotvorb še niso potrdili. Okužbo z virusom najlaže dokažemo s spremljanjem serološkega profila; virus lahko dokažemo tudi z monoklonskimi protitelesi in z molekularno biološkimi metodami"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-ZYCV7PXN","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-ZYCV7PXN"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-ZYCV7PXN/277e10be-c49e-4168-bb78-54d27be1c5bf/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-ZYCV7PXN/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-ZYCV7PXN"}}}}