ANNALES KINESIOLOGIAE • 14 • 2023 • 2 129 Review article DOI: https://doi.org/10.35469/ak.2023.389 received: 2023-04-20 UDC: 796.015:616.12-008.33-053.9 THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE OF THE ELDERLY: A SYSTEMATIC REVIEW Doroteja RANČIĆ 1 , Tamara ILIĆ 1 , Stefan STOJANOVIĆ 1 1 Faculty of sport and physical education, University of Niš Corresponding author: Doroteja RANČIĆ 1 Faculty of Sport and Physical Education, University of Niš Čarnojevića 10A, 18000 Niš, Serbia Telephone number: +381652644224 Email: doroteja.r@yahoo.com ABSTRACT Purpose: The aim of this review was to determine the influence of physical activity on the arterial blood pressure of the elderly through a review of previous research. Methods: The search was performed on the Web of Science, Google Scholar and PubMed databases. The first search identified 1112 articles. In the initial assessment carried out in accordance with the inclusion and exclusion criteria, 15 articles were found suitable and were included in the study, while 1097 studies were excluded. The search was limited to articles published in period of 2002–2022. Results: After the applied exercise programs and evaluation at the final measure- ments, the mean values of systolic blood pressure, on the total sample, were 131 mmHg, while the values of diastolic blood pressure were 77 mmHg, which indicates that physi- cal activity (regardless of whether swimming, walking, yoga, resistance training, high interval training, Tai Chi) have a positive effect on the arterial blood pressure of the elderly. Conclusion: All studies, except one, showed a positive influence of physical activity on the arterial blood pressure of elderly people. In this regard, it can be concluded that physical activity, regardless of the type of activity, has a positive effect on the arterial blood pressure of the elderly, in the form of a reduction in blood pressure values. Keywords: physical activity, arterial blood presure, elderly. 130 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 ANNALES KINESIOLOGIAE • 14 • 2023 • 2 VPLIV TELESNE DEJA VNOSTI NA ARTERIJSKI KRVNI TLAK PRI STAREJŠIH OSEBAH: SISTEMATIČNI PREGLED IZVLEČEK Namen: Namen te analize je bil s pregledom dosedanjih raziskav ugotoviti vpliv telesne dejavnosti na arterijski krvni tlak pri starejših osebah. Metode: Iskanje je potekalo v podatkovnih zbirkah Web of Science, Google Scholar in PubMed. Pri prvem iskanju je bilo opredeljenih 1112 člankov. Pri začetni presoji, opravljeni v skladu z merili za vključitev in izključitev, se je 15 člankov izkazalo za primerne in so bili vključeni v študijo, medtem ko je bilo 1097 študij izključenih. Iskanje je bilo omejeno na članke, objavljene v obdobju 2002–2022. Rezultati: Po izvedenih vadbenih programih in oceni ob končnih meritvah so bile povprečne vrednosti SKT na celotnem vzorcu 131 mmHg, vrednosti DKT pa 77 mmHg, kar kaže, da imajo telesne dejavnosti (ne glede na to, ali gre za plavanje, hojo, jogo, vadbo vzdržljivosti, visoko intervalni trening, tai chi) pozitiven učinek na arterijski krvni tlak starejših oseb. Sklep: Vse študije, razen ene, so pokazale pozitiven vpliv telesne dejavnosti na ar- terijski krvni tlak starejših oseb. V zvezi s tem lahko sklepamo, da ima telesna de- javnost, ne glede na vrsto dejavnosti, pozitiven učinek na arterijski krvni tlak starejših, in sicer v obliki zmanjšanja vrednosti krvnega tlaka. Ključne besede: telesna dejavnost, arterijski krvni tlak, starejše osebe. ANNALES KINESIOLOGIAE • 14 • 2023 • 2 131 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 INTRODUCTION Aging is a natural process of life characterized by specific physical, psy- chological, and social changes (Hamidizadeh, Ahmadi & Fallahi, 2004). In addition, aging refers to irreversible degenerative changes that are generally progressive, in which the physical condition of an older individual deteriorates, along with their ability and motivation to engage in physical activity (Fiori, Smith & Antonucci, 2007). As a result, practically all organs in most elderly people experience some degree of degradation/atrophy in their morphologi- cal forms or in the tasks they perform in the body. As a result, various chronic diseases appear in older individuals, including cardiovascular diseases such as hypertension, coronary artery diseases, and skeletal diseases such as arthritis, osteoporosis, and cancer (Hamidizadeh et al., 2004). Arterial blood pressure (BP) is an important indicator of cardiovascular health, and hypertension (high blood pressure) is a major risk factor for the development of cardiovascular disease in the elderly (Chobanian et al., 2003). The risk of hy - pertension tends to be greater in elderly, and it is one of the diseases that can be treated. Physical activity is a well-established lifestyle factor that can lower blood pressure levels and reduce the risk of hypertension in older adults (Cornelissen & Smart, 2013; Pescatello, MacDonald, Lamberti, & Johnson, 2015). However, the relationship between physical activity levels and blood pressure in older adults is complex, and the optimal amount and intensity of physical activity required to achieve blood pressure reduction is still unclear (Pescatello et al., 2015). In addi- tion, other factors such as age, gender, body mass index, and comorbidities such as diabetes and chronic kidney disease may influence the relationship between physical activity levels and blood pressure in the elderly. Therefore, it is impor - tant to investigate the effect of physical activity on blood pressure in the elderly while controlling for these confounding variables. Several studies have examined the impact of physical activity levels on BP in older adults, with some showing a significant association between higher physical activity levels and lower BP (Pescatello et al., 2015), while others have reported mixed or non-significant findings (Cornelissen & Smart, 2013; Graca et al., 2022 ). Moreover, some studies suggest that a sedentary lifestyle increases the risk of hypertension, while increased physical activity at work or leisure is associated with lower blood pressure values (Kokkinos, Papademetriou, 2000). The effect of aerobic exercise on hypertension was mainly tested in long-term exercise programs (at least three months) with high intensity and a large num- ber of sessions per week (5 days per week). In a study by Moraes et al. (2012), the intervention group’s mean systolic and diastolic blood pressure decreased 132 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 ANNALES KINESIOLOGIAE • 14 • 2023 • 2 by 3 mmHg and 1 mmHg, respectively, after three days of aerobic exercise per week for three months, but the control group’s mean blood pressure showed no significant change. The short-term program had no effect on lowering systolic blood pressure, but it did lower diastolic blood pressure, according to a study by Tabara et al. (2007) comparing aerobic short-term and long-term exercise programs with mild and moderate intensities on cardiovascular indicators of older adults. Mean systolic and diastolic blood pressure decreased throughout time, from 136 mmHg to 129 mmHg, and 87 mmHg to 83 mmHg, respectively. Based on a review of the literature, we can conclude that the previous studies are not sufficiently balanced and that there are many dilemmas about the influ - ence of physical activity on the arterial pressure of the elderly. This study investi- gated the effects of multiple types of physical activity on arterial blood pressure in the elderly. Knowing the effect of physical activity on the arterial blood pressure of the elderly, this paper contributes by sublimating the evidence and showing the effect of physical activity on blood pressure. In this context, we assume that in- dividuals who had higher level of physical acitivity would have preferable, that is lower SBP and DBP, BP values. Although the work is not unique, it represents ev - idence-based evidence of the importance of physical activity for blood pressure. Also, most systematic reviews focus on the study of one type of physical activity, while showing the importance of multiple types of physical activity gives impor- tance in planning physical activity programs in order to regulate blood pressure, where it is possible to make the program more flexible. Therefore, the aim of this study was to determine the influence of physical activity on the arterial blood pressure of the elderly through a review of previ- ous research. METHODS This study was designed using the systematic review technique. Research data was collected considering the inclusion and exclusion criteria of the stud- ies published, as a result of the search made by using the keywords “physical activity, artirial blood presure, eldery” in English. The search was performed on the Web of Science, Google Scholar and PubMed databases. In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, a systematic review of the available literature was un- dertaken (Moher, Liberati, Tetzlaff & Altman, 2009) (Figure 1.). The first search identified 1112 articles. In the initial assessment carried out in accordance with the inclusion and exclusion criteria, 15 articles were found to be suitable and ANNALES KINESIOLOGIAE • 14 • 2023 • 2 133 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 were included in the study, while 1097 studies were excluded. In order for a study to be included in the analysis, it had to meet the following criteria: year of publication (2002–2022), participants were eldery people (≥50 yrs), also the studies that were included in this review had to be based on the influence of physical activity on the arterial blood pressure of the elderly. References from all papers were reviewed in order to find more studies that dealt with topics that were of interest and related to our review paper. Figure 1. PRISMA flow chart of article selection process RESULTS In this part, 15 original scientific studies are presented on the topic of the influence of physical activity on the arterial blood pressure of the elderly in Table 1. Included Analysis Identification Eligibility Artcles identified through a database search n = 1112 Articles (duplicates) removed n = 510 Articles included in systematic review n = 15 Excluded (no full text available) n = 538 Eliminated articles for non-compliance to including criteria n = 49 Articles analyzed n = 602 Full text articles assessed for eligibility n = 64 134 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 ANNALES KINESIOLOGIAE • 14 • 2023 • 2 Table 1. Systematic review of the studies Аuthors Participants Experimental program Mean SBP (Before intervention) Mean DBP (After intervention) Results Tabara et al. (2007) n = 139 2 groups Age 67±6 Mild to moderate aerobic exercise for 30 minutes 2/week for 6 months 136 mmHg 75 mmHg 129 mmHg 70 mmHg Both SBP and DBP were significantly reduced Kawasaki et al. (2011) n = 35 2 groups Age 57–73 6-month exercise program (swimming) 2/week 136 mmHg 81 mmHg 132 mmHg 77 mmHg The exercise program significantly improved SBP and DBP, as did lipid and glucose metabolism Pitsavos et al. (2011) n = 42 2 groups Age 53 ± 7 Aerobic exercise program for 16 weeks, 3/week, with 60 to 80 max. heart rate 131 mmHg 83 mmHg 119 mmHg 76 mmHg This study showed a positive effect of regular exercise on SBP and DBP Habib et al. (2014) n = 92 2 groups Age 65–75 4-week period of walking, 3/ week, each time for 20–30 minutes 149 mmHg 94 mmHg 144 mmHg 85 mmHg The findings showed that walking is effective in reducing blood pressure in the elderly Miura et al. (2015) n = 200 2 groups Age 60–88 12-week program (90 minutes 2/week), 6–8 resistance exercises, circuit training and chair exercises for the lower body 150 mmHg 84 mmHg 145 mmHg 80 mmHg Both groups had reductions in SBP and DBK (group doing circuit training and group doing lower body chair exercises) Patil et al.(2015) n = 60 2 groups Age ≥60 Yoga training and brisk walking with stretching exercises 1 hour in the morning 6/week for 12 weeks 146 mmHg 74 mmHg 133 mmHg 73 mmHg Yoga was more effective than brisk walking in reducing SBP and DBP ANNALES KINESIOLOGIAE • 14 • 2023 • 2 135 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 Аuthors Participants Experimental program Mean SBP (Before intervention) Mean DBP (After intervention) Results Ardakani et al. (2018) n = 24 2 groups Age 67.37 8 weeks of resistance training, 3/week with 40–65% intensity + one max. repetition 143 mmHg 72 mmHg 138mmHg 70mmHg Resistance training for 8 weeks reduced SBP to a greater extent than DBP Wong et al. (2018) n = 100 2 groups Age~74 Swimming 3–4/week for a period of 20 weeks 147 mmHg 92 mmHg 143mmHg 86 mmHg Swimming led to a decrease in blood pressure while increasing strength and aerobic capacity in women Amooali et al. (2019) n = 40 2 groups Age 50–70 Aerobic exercises performed 3 times a week for 12 weeks 145 mmHg 86 mmHg 140 mmHg 81 mmHg Aerobic exercise for 12 weeks was effective in reducing SBP and DBP Ruangthai & Phoemsapthawee (2019) n = 54 3 groups Age 67±5.8 Supervised exercise training (1- hour sessions, 3 times a week for 12 weeks), (strength and endurance training + combined) 146 mmHg 84 mmHg 141mmHg 76 mmHg Both types of training, as well as the combination of the two, led to a decrease in SBP and DBP Herrod et al. (2020) n = 48 4 groups Age 71.0 HIIT on a cycle ergometer; isometric handgrip training (IHG); unilateral, upper limb remote ischemic preconditioning (RIPC) or non intervention control HIIT 142 mmHg 85 mmHg IHG 139 mmHg 83 mmHg HIIT 131 mmHg 82 mmHg IHG 131 mmHg 75 mmHg 6 weeks of fully supervised HIIT or IHG can reduce the resting SBP of older adults by an average of 9 mmHg 136 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 ANNALES KINESIOLOGIAE • 14 • 2023 • 2 Аuthors Participants Experimental program Mean SBP (Before intervention) Mean DBP (After intervention) Results Choi et al. (2020) n = 27 2 groups Age 72–77 Elastic band exercises (EBE) for 60 min, 3/week for 3 months. The exercises consisted of incremental resistance and aerobic exercises. 126 mmHg 78 mmHg 121 mmHg 75 mmHg Resting SBP and DBP were significantly reduced by ~5.0 mmHg after the 12-week EBE program Iellamo et al. (2021) n = 36 3 groups Age ≥ 60 Aerobic continuous exercise (ACE), HIIT, and combined (aerobic and resistance) exercise (CE) ACE 121 mmHg 81 mmHg CE 121 mmHg 82 mmHg ACE 115 mmHg 78 mmHg CE 114 mmHg 78 mmHg SBP lowering significant in the ACE and CE groups but not in the HIIE group. In all groups, DBP decreased to a similar level, although not significantly. Wen & Su (2021) n = 66 2 groups Age 50–75 60 minutes of simplified Tai Chi (STC) 3/week for 6 weeks or 60 min of Wu-style Tai Chi (WTC) 3/ week for 6 weeks STC 134 mmHg 80 mmHg WTC 136 mmHg 80 mmHg STC 124 mmHg 77 mmHg WTC 123 mmHg 76 mmHg Results showed that compared with simplified Tai Chi, Wu-style Tai Chi had a better effect on BP in the elderly −5.80 (mmHg) Graça et al. (2022) n = 32 2 groups Age 55–72 Resistance training followed by HIIT or vice versa (8 weeks) 119 mmHg 80 mmHg 114 mmHg 74 mmHg Blood pressure did not change significantly following the intervention for either group Legend: Mean BP – arterial blood pressure before the exercise program (mean values); Mean BP – arterial blood pressure after the exercise program (mean values); n – number of participants; SBP – systolic blood pressure; DBP – diastolic blood pressure. ANNALES KINESIOLOGIAE • 14 • 2023 • 2 137 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 DISSCUSION Hypertension is a serious public health challenge worldwide, being quan- titatively the major risk factor for premature cardiovascular disease (Angeli, Reboldi & Verdecchia, 2013). If the underlying problem is not prevented or treated, many patients with hypertension die from hypertension-related diseas- es. Therefore, the aim of this review was to determine the influence of physi- cal activity on the arterial blood pressure of the elderly, regardless of gender, through a review of previous research. In the selected studies, there was usually one group that had to fulfill the conditions (the elderly population) in order to participate in the study. The num- ber of participants varied from study to study, the smallest number of partici- pants was included in our study (Ardakani, Qassemian, Koushki, Shakour & Mehrez, 2018) had a sample of only 24 elderly people, and the largest number (Miura, Takahashi, Maki, & Sugino, 2015) as many as 200 elderly people. The total number of participants in the present study amounted to 995 elderly peo- ple between the ages of 50 and 88. Data from all the studies presented show that the mean values of systolic blood pressure (SBP) before exercise, in the total sample, were 138 mmHg, while the mean values of diastolic blood pressure (DBP) before exercise were 82 mmHg. After the exercise programs and evaluation at the final measure- ments, the mean values of SBP, on the total sample, were 131 mmHg, while the values of DBP were 77 mmHg, which indicates that physical activities (re- gardless of whether swimming, walking, yoga, resistance training, high interval training or Tai Chi) have a positive effect on the arterial blood pressure of the elderly. When it comes to physical activity, people who exercised more frequently and for a longer period of time had better improvements in the mean values of arterial blood pressure compared to people who did not exercise, i.e. sedentary individuals from control groups in the presented studies (Habib, Fariba, Fari- deh, Navideh & Saeed, 2014; Kawasaki, Sullivan, Ozoe, Higaki & Kawasaki, 2011; Wong et al., 2019; Ardakani et al., 2018; Pitsavos et al., 2011; Patil, Aithala & Das, 2015; Amooali, Daryanoosh, Baigi & Mohamadi, 2019). It is clear that all forms of physical activity have a positive effect on arterial blood pressure, with significant improvements observed after the swimming program (Kawasaki et al., 2011; Wong et al., 2019), walking / brisk walking program (Amooali et al., 2019; Pitsavos et al., 2011; Patil et al., 2015; Habib et al., 2014; Tabara et al., 2007; Iellamo et al., 2021), and resistance training (Ruangthai & Phoemsapthawee 2019; Miura et al., 2015; Ardakani et al., 2018; Choi, Hurr & 138 Doroteja RANČIĆ, Tamara ILIĆ, Stefan STOJANOVIĆ: THE INFLUENCE OF PHYSICAL ACTIVITY ON THE ARTERIAL BLOOD PRESSURE ..., 129–141 ANNALES KINESIOLOGIAE • 14 • 2023 • 2 Kim, 2020), with the same positive effects being observed in the study by Wen & Su (2021) that implemented simplified Tai Chi and Wu-style Tai Chi and Patil et al. (2015) who implemented yoga sessions (Patil et al., 2015). Only one study did not find significant changes in SBP or DBP after intervention (Graça et al., 2022), in which they implemented resistance traning and high-intensity interval training for 8 weeks. A total of 14 out of 15 studies shown in the table showed positive results of physical activity on arterial blood pressure and in this connection we can conclude that physical activity, in general, has a positive effect on the arterial blood pressure of the elderly. CONCLUSION Physical activity (regardless of whether swimming, walking, yoga, resis- tance training, high interval training or Tai Chi) has a positive effect on the arterial blood pressure of the elderly. With the exception of one study, all the other studies reviewed demonstrated a beneficial impact of physical activity on the arterial blood pressure of elderly individuals. In light of this, it can be concluded that physical activity, regardless of type of activity, yields favorable results by lowering blood pressure values in the elderly population. Limitations of the study This study has potential limitations. The study’s stringent inclusion and ex- clusion criteria may have limited the amount of literature gathered. Addition- ally, the heterogenity of studies included in this systematic review indisposed us of performing meta-analysis. Also, there are numerous internal and external factors, such as gender, age, level of metabolical health, stress etc., that can affect BP values, but the analyzed studies did not take into account all these variables. Acknowledgement All authors equally contributed in preparation of this manuscript. 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